TITLE

EFFECTS OF PLUMERIA OBTUSA LINN. IN PEPTIC ULCER INDUCED BY PYLORUS LIGATION & INDOMETHACIN

AUTHOR(S)
Singh, Amit Pratap; Shukla, Vaibhav; Khare, Piuesh
PUB. DATE
March 2012
SOURCE
Journal of Pharmaceutical & Scientific Innovation;Mar/Apr2012, Vol. 1 Issue 2, p26
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Peptic ulcer disease refers to pathological lesions and ulcers of any portion of gastrointestinal tract exposed to acid activated pepsin. Gastric ulcer refers to ulcer in the stomach where as duodenal ulcer is a ulcer found in duodenum of small intestine. Helicobacter pylori infection, a spiral shaped type of bacteria, is present in more than 90% of the patients with intestinal ulcers and more than 80% of patients with stomach ulcers. Helicobacter pylori weaken the protective mucous coating of the stomach and duodenum which allows acid to get through to the sensitive lining beneath. Both the acid and the bacteria irritate the lining and cause a sore, or ulcer. Long term use of anti inflammatory drugs (NSAIDs) or pain relievers such as aspirin, ibuprofen, and naproxen sodium. NSAIDs lower the stomach's resistance to the harmful effects of acid. Effects of Plumeria obtusa linn. was observed in peptic ulcer induced by pylorus ligation & indomethacin.
ACCESSION #
85289607

 

Related Articles

  • Bacteria Usually Don't Block the Outlet. Thompson, Jon S. // American Journal of Gastroenterology;Nov2000, Vol. 95 Issue 11, p3031 

    Discusses research being done on the association of gastric outlet obstruction resulting from peptic ulcer disease requiring surgical intervention with Helicobacter pylori infection. Reference to a study by J. B. Gibson et al., published in a 2000 issue of the "Journal of American College...

  • Percentage Changes in Serum Pepsinogens Are Useful as Indices of Eradication of Helicobacter pylori. Furuta, Takahisa; Kaneko, Eiza; Baba, Satoshi; Arai, Hajime; Futami, Hajime // American Journal of Gastroenterology;Jan1997, Vol. 92 Issue 1, p84 

    Objective: Eradication of Helicobacter pylori has been gaining significance for the treatment of gastroduodenal diseases. Establishment of a precise diagnostic method for H. pylori is of great value. The aim of this study was to establish a new method for precisely judging the...

  • Peptik Ãœlser ve Gastrit Saptanan Hastalarda Helicobacter Pylori Sıklığı. EMRE, Emre; AHISHALI, Emel; DOLAPÇIOĞLU, Can; SÜMER EMRE, Şahika; HALLAÇ KESER, Sevinç; DABAK, Reşat; UYGUR BAYRAMİÇLİ, Oya // Journal of Kartal Training & Research Hospital / Kartal Egitim v;2013, Vol. 24 Issue 2, p87 

    Background: Recent studies report that there has been an increase in the incidence of Helicobacter pylori (HP)-negative peptic ulcer disease. In this study, we investigated the frequency of HP among patients with peptic ulcer and gastritis. Methods: In this study, endoscopy reports of 2500...

  • GASTROINTESTINAL TRACT.  // Nurse Practitioners Prescribing Reference;Summer2010, Vol. 17 Issue 2, p147 

    The article offers information on several medicines used to treat gastrointestinal tract infections. It says that Amoxil from GlaxoSmithKline with lansoprazole and/or clarithromycin can eliminate helicobacter pylori while Bentyl from Axcan Pharma is used for irritable bowel syndrome....

  • Helicobacter pylori: current status and future prospects. O'Mahony, Rachel; Vaira, Dino; Holton, John; Basset, Christelle // Science Progress;Nov2004, Vol. 87 Issue 4, p269 

    Helicobacter pylori is a global pathogen that causes severe gastrointestinal diseases leading to a significant morbidity and mortality. There is an effective treatment for peptic ulcer disease, however, this is being compromised by an increase in the prevalence of antibiotic resistance. Although...

  • An evidence-based approach the management of uninvestigated dyspepsia in the era of Helicobacter pylori. Veldhuyzen van Zanten, Sander J.O.; Flook, Nigel; Chiba, Naoki; Armstrong, David; Barkun, Alan; Bradette, Marc; Thomson, Alan; Bursey, Ford; Blackshaw, Patricia; Frail, Dawn; Sinclair, Paul // CMAJ: Canadian Medical Association Journal Supplement;6/13/2000 Dyspepsia, Vol. 162 Issue 12, pS3 

    AbstractObjectives: To provide Canadian primary care physicians with an evidence-based clinical management tool, including diagnostic and treatment recommendations, for patients who present with uninvestigated dyspepsia.Recommendations: The management tool has 5 key decision steps addressing the...

  • Virulence attributes of Helicobacter pylori isolates & their association with gastroduodenal disease. Saxena, A.; Shukla, S.; Prasad, K. N.; Ghoshal, U. C. // Indian Journal of Medical Research;May2011, Vol. 133 Issue 5, p514 

    Background & objectives: Certain genotype(s) of Helicobacter pylori strains may play important role in the development of gastric cancer (GC) and peptic ulcer disease (PUD). This study was undertaken to investigate the association of cagA, cagA3/ region subtypes, babA2 and vacA genotypes of H....

  • Eating Habits a Risk Factor to Peptic Ulcer. Mahmood, Khawaja T.; Sara, S.; Shifa, H. // Journal of Pharmaceutical Sciences & Research;2011, Vol. 3 Issue 1, p903 

    The dietary habits influencing the risk of acquisition of Helicobacter pylori infection resulting in peptic ulcer are not well established. 30 patients requiring an endoscopy for the evaluation of gastrointestinal symptoms had demographic and dietary data collected and biopsy specimens of the...

  • Stress and diet do not cause ulcers, bacteria does.  // Executive Health's Good Health Report;Nov95, Vol. 32 Issue 2, p2 

    Explains that the Helicobacter pylori bacterium causes peptic ulcers, and not stress or diet, as believed by most Americans with digestive disorders. Three causes of ulcers; Description of H. pylori; Treatment of H. pylori caused ulcers with antibiotics.

Share

Read the Article

Courtesy of NEW JERSEY STATE LIBRARY

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics