Extent of ST-Segment Depression Predicts In-Hospital Outcome in Non ST-Segment Elevation Acute Coronary Syndrome

Khan, M. R.; Haq, M. A.; Majumder, N. K.; Hossain, M. M.; Rahman, Z.; Rahman, M. T.; Akanda, A. K.; Mohibullah, A. K. M.
July 2012
Cardiovascular Journal;Jul2012, Vol. 5 Issue 1, p62
Academic Journal
Background: The presence of ischemic ECG changes on admission has been shown to predict outcome, the relationship between the extent of ECG changes and the risk of cardiac events is still ill defined. The severity of ST-segment depression on admission ECG has a strong association with adverse in-hospital outcome in patients with non ST-segment elevation acute coronary syndrome. The study was done to observe the extent of ST-segment depression and in-hospital outcome in patients with non ST-segment elevation acute coronary syndrome. Methods: This study was conducted in the Department of Cardiology in NICVD Dhaka, from January 2006 to December 2007. Considering inclusion and exclusion criteria, a total of 183 patients were evaluated. All the patients were evaluated clinically after admission. ECG, blood biochemistry and echocardiography were done. Patients were categorized into three groups according to the extent of ST- segment depression. Results: In this study, analysis of the baseline parameters revealed no statistically significant difference among the three groups of patients (p>0.05). Mean sum of the ST-segment depression analysis was done and all mean values were more in group III patients. 41.0% patients developed complications during the study period. Acute LVF (22.9%) was the most common complication followed by arrhythmia (11.5%), cardiogenic shock (4.4%) and STEMI (2.2%). All the complications were more in group III patients. During this period 6% patients died and more death (12.3%) was observed in group III patients. Conclusion: The amount of ST-segment depression is a powerful predictor of adverse in-hospital outcome in patients with non ST-segment elevation acute coronary syndrome.


Related Articles

  • Impact of Transesophageal Electrophysiologic Study to Elucidate the Mechanism of Arrhythmia on Children With Supraventricular Tachycardia and No Preexcitation. Brembilla-Perrot, Béatrice; Moulin-Zinsch, A.; Sellal, J.; Schwartz, J.; Olivier, A.; Zinzius, P.; De Chillou, C.; Beurrier, D.; Rodermann, M.; Goudote, G.; Al Amoura, H.; Terrier de la Chaise, A.; Lemoine, J.; Rizk, J.; Lethor, J.; Anne Tisserand, J.; Taïhi, S.; Marçon, F. // Pediatric Cardiology;Oct2013, Vol. 34 Issue 7, p1695 

    An electrophysiologic study (EPS) of children and teenagers with paroxysmal supraventricular tachycardia (SVT) and normal electrocardiography (ECG) in sinus rhythm was evaluated. Generally, EPS is performed only before paroxysmal SVT ablation in these patients. In this study, 140 patients (mean...

  • Sex as a determinant of prehospital ECG in ST- and non-ST elevation myocardial infarction patients. Klerda, Kristina; Varenhorst, Christoph; James, Stefan; Alfredsson, Lars; Blomberg, Hans; Moradi, Tahereh // Heart;Nov2014, Vol. 100 Issue 22, p1817 

    A letter to the editor is presented in response to the article "Effects of prehospital 12-lead ECG on processes of care and mortality in acute coronary syndrome: A linked cohort study from the Myocardial Ischaemia National Audit Project" by T. Quinn and colleagues in the 2014 issue.

  • Arritmias ventriculares y nuevo síndrome coronario agudo en pacientes con infarto y dispersión del intervalo QT prolongado. González, Fernando Rodríguez; González, Elibet Chávez; de J. Machín Cabrera, Wilfredo; Reyes Hernández, Luis M.; Ferrer, Vielka González // CorSalud;2013, Vol. 5 Issue 1, p101 

    Introduction and Objective: Myocardial ischemia increases QT dispersion in the elec-trocardiogram because, in these circumstances, the action potential duration de-creases in the ischemic insult area by creating a dispersion of repolarization. The rapid succession of local metabolic and ionic...

  • Rhythm changes and the function of the left ventricle: analysis of effects on the left ventricular ejection fraction. Ferati, Fatmir // Cardiologia Croatica;Mar/Apr2013, Vol. 8 Issue 3/4, p88 

    The purpose of the case report is the analysis of the effects of rhythm changes on ejection fraction (EF) of the left ventricle (LV), which can be determined by transthoracal echocardiography. For this purpose, we have analyzed five patients with different rhythm changes. From three of them the...

  • Wellen's T Waves and U Waves in Acute Coronary Syndrome. Lebehn, Mark; Osamu Fukuyama; Joven, Mark // Hawaii Journal of Medicine & Public Health;Sep2013 Supplement 4, Vol. 72 Issue 9, p57 

    Introduction: The most common electrocardiographic (EKG) finding suggestive of acute severe ischemia is development of the ST segment depression. Although this is the most sensitive EKG marker for transient ischemia, ST segment depression cannot reliably identify the location of the ischemia in...

  • The Additive Value of 2D Longitudinal Strain During Stress Echocardiography in Coronary Artery Disease Detection in Low Risk Acute Coronary Syndrome - A Pilot Study. Onuå, Roxana; Onciul, Sebastian; Marinescu, Cristina; Zamfir, Diana; Dorobanåu, Maria // Medicina Moderna;2015, Vol. 22 Issue 3, p235 

    echocardiography and discuss the pathophysiological base and the role of LS alterations in coronary artery disease (CAD) detection. Methods: We performed stress echocardiography 24 hours after admission in 10 patients presented with acute chest pain (ACP), stratified as low risk acute coronary...

  • Considerations in the Diagnosis and Emergency Management of Pediatric Tachycardias. Bhat, Sundeep R.; Miyake, Christina; Wang, N. Ewen; Madhok, Manu // Pediatric Emergency Medicine Reports;Aug2012, Vol. 17 Issue 8, p93 

    Cardiac dysrhythmias in children may be due to primary conduction abnormalities or may occur in the setting of structural heart disease, metabolic derangements from toxic ingestions, or infections. Supraventricular tachycardias (SVT) represent the most common pediatric dysrhythmias in...

  • Management of resistant supraventricular tachycardia in the immediate postpartum period: A case report. Narasimhaiah, Gangadharaiah; Srinivasan, Nataraj M.; Hemadribotla, Aruna; Ramaiah, Renuka // Journal of Obstetric Anaesthesia & Critical Care;Jul-Dec2013, Vol. 3 Issue 2, p91 

    Supraventricular tachycardia (SVT) during pregnancy or immediate postpartum is the commonest arrhythmia during pregnancy. Usually, the clinical symptoms are mild or go unrecognized. Rarely as in our case, can patient present with severe symptoms of agitation and restlessness which can mimic...

  • Appropriate threshold levels of cardiac beat-to-beat variation in semi-automatic analysis of equine ECG recordings. Flethøj, Mette; Kanters, Jørgen K.; Pedersen, Philip J.; Haugaard, Maria M.; Carstensen, Helena; Olsen, Lisbeth H.; Buhl, Rikke // BMC Veterinary Research;11/28/2016, Vol. 12, p1 

    Background: Although premature beats are a matter of concern in horses, the interpretation of equine ECG recordings is complicated by a lack of standardized analysis criteria and a limited knowledge of the normal beat-to-beat variation of equine cardiac rhythm. The purpose of this study was to...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics