TITLE

Small RNA: Long-lived microRNA complexes

AUTHOR(S)
Muers, Mary
PUB. DATE
February 2013
SOURCE
Nature Reviews Genetics;Feb2013, Vol. 14 Issue 2, p78
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses a research entitled "Long-lived microRNA-Argonaute complexes in quiescent cells can be activated to regulate mitogenic responses," by S. H. Olejniczak, which suggested that miRNA complexes could allow cells to retain long-term information for post-transcriptional regulation.
ACCESSION #
84942418

 

Related Articles

  • Transcribe this way: Rap1 confers promoter directionality by repressing divergent transcription. Wu, Andrew C.K.; Van Werven, Folkert J. // Transcription (2154-1264);Jun2019, Vol. 10 Issue 3, p164 

    In eukaryotes, divergent transcription is a major source of noncoding RNAs. Recent studies have uncovered that in yeast, the transcription factor Rap1 restricts transcription in the divergent direction and thereby controls promoter directionality. Here, we summarize these findings, propose...

  • Panning for Long Noncoding RNAs. Shanshan Zhu; Xiao-Ou Zhang; Li Yang // Biomolecules (2218-273X);Mar2013, Vol. 3 Issue 1, p226 

    The recent advent of high-throughput approaches has revealed widespread transcription of the human genome, leading to a new appreciation of transcription regulation, especially from noncoding regions. Distinct from most coding and small noncoding RNAs, long noncoding RNAs (lncRNAs) are generally...

  • Computational Identification of Novel MicroRNAs and Their Targets in Vigna unguiculata. Yongzhong Lu; Xiaoyun Yang // Comparative & Functional Genomics;2010, Special section p1 

    MicroRNAs (miRNAs) are a class of endogenous, noncoding, short RNAs directly involved in regulating gene expression at the posttranscriptional level. High conservation of miRNAs in plant provides the foundation for identification of new miRNAs in other plant species through homology alignment....

  • Gene expression: Revealing truths about non-coding transcripts. Skipper, Magdalena // Nature Reviews Genetics;Apr2004, Vol. 5 Issue 4, p246 

    The article discusses research being done on non-coding RNA (ncRNA). It references a study by S Cawley et al, published in a previous issue of "Cell." The study used a combination of high-density oligonucleotide arrays and chromatin immunoprecipitation to look for the binding sites of three...

  • Epigenetic Control of MicroRNA Expression and Aging. Liang, Ruqiang; Bates, David J.; Wang, Eugenia // Current Genomics;May2009, Vol. 10 Issue 3, p184 

    MicroRNAs are a major category among the noncoding RNA fraction that negatively regulate gene expression at the post-transcriptional level, by either degrading the target messages or inhibiting their translation. MicroRNAs may be referred to as ‘dimmer switches’ of gene expression,...

  • PPARα Is Regulated by miR-21 and miR-27b in Human Liver. Kida, Katsuhiko; Nakajima, Miki; Mohri, Takuya; Oda, Yuki; Takagi, Shingo; Fukami, Tatsuki; Yokoi, Tsuyoshi // Pharmaceutical Research;Oct2011, Vol. 28 Issue 10, p2467 

    Purpose: Peroxisome proliferator-activated receptor α (PPARα) is an important transcriptional factor that regulates genes encoding endo/xenobiotic enzymes and lipid metabolizing enzymes. In this study, we investigated whether microRNAs (miRNAs) are involved in the regulation of PPARα in...

  • Emerging Roles of Small Epstein-Barr Virus Derived Non-Coding RNAs in Epithelial Malignancy. Raymond Wai-Ming Lung; Joanna Hung-Man Tong; Ka-Fai To // International Journal of Molecular Sciences;Sep2013, Vol. 14 Issue 9, p17378 

    Latent Epstein-Barr virus (EBV) infection is an etiological factor in the progression of several human epithelial malignancies such as nasopharyngeal carcinoma (NPC) and a subset of gastric carcinoma. Reports have shown that EBV produces several viral oncoproteins, yet their pathological roles...

  • Arabidopsis Non-Coding RNA Regulation in Abiotic Stress Responses. Akihiro Matsui; Anh Hai Nguyen; Kentaro Nakaminami; Motoaki Seki // International Journal of Molecular Sciences;Nov2013, Vol. 14 Issue 11, p22642 

    Plant growth and productivity are largely affected by environmental stresses. Therefore, plants have evolved unique adaptation mechanisms to abiotic stresses through fine-tuned adjustment of gene expression and metabolism. Recent advanced technologies, such as genome-wide transcriptome analysis,...

  • Maintenance of epigenetic information: a noncoding RNA perspective. Mondal, Tanmoy; Kanduri, Chandrasekhar // Chromosome Research;Dec2013, Vol. 21 Issue 6/7, p615 

    Along the lines of established players like chromatin modifiers and transcription factors, noncoding RNA (ncRNA) are now widely accepted as one of the key regulatory molecules in epigenetic regulation of transcription. With increasing evidence of ncRNAs in the establishment of gene silencing...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics