LHR Gene Expression in Human Granulosa Cells

Yding Andersen, Claus
January 2013
Fertility Weekly;1/14/2013, p5
Academic Journal
The article reports on the results of a study led by J. V. Jeppesen on luteinizing hormone receptor (LHR) gene expression in human granulosa cells (GC). It discusses how the study was conducted which included 150 small antral follicles from 61 women who are undergoing ovarian cryopreservation of ovarian tissue. The results reportedly revealed that the LHR gene is expressed in human GC for the whole follicular phase.


Related Articles

  • Mouse Ovarian Tissue Cryopreservation Has Only a Minor Effect on In Vitro Follicular Maturation and Gene Expression. Hung-Ching Liu; Zhiming He, Larry I.; Rosenwaks, Zev // Journal of Assisted Reproduction & Genetics;Oct2003, Vol. 20 Issue 10, p421 

    Purpose: To establish a protocol for ovarian tissue cryopreservation which can retain fertility potential after thawing and to evaluate the impact of cryopreservation on development and gene expression during folliculogenesis. Methods: A controlled randomized study in a clinical and academic...

  • Evaluation of MMP-2 gene expression in mice pre-antral follicles derived from vitrified and fresh ovarian tissue. Khosravi, S.; Zavareh, S.; Paylakhi, S.; Gorbanian, M. // Iranian Journal of Reproductive Medicine;Jun2014 Supplement, Vol. 12, p84 

    Introduction: Cryopreservation is a useful method for preservation of ovarian tissue of patients who are candidate for chemo and radiotherapy. It has been postulated that MMP-2 participates in the process of remodeling of ovarian extracellular matrix such as the follicle growth and ovulation....

  • OPTIMUM FOR CRYOPRESERVATION OF HUMAN OVARIAN TISSUE: GENE EXPRESSION AS A DETECTOR OF EFFECTIVENESS. Isachenko, V.; Lapidus, I.; Isachenko, E.; Hancke, K.; Nawroth, F.; Wiegratz, I.; Kreienberg, R. // Reproductive BioMedicine Online (Reproductive Healthcare Limited;Oct2010 S3 Supplemen, Vol. 20, pS54 

    Objective: Cryopreservation, the most important stage of the cryobanking of ovarian tissue, can be carried out using one of two methods: conventional ("slow") freezing, and vitrification (direct plunging into liquid nitrogen). For human oocytes vitrification is more effective compared to...

  • Cryopreservation of Ovarian Tissue in Pediatric Patients. Fabbri, R.; Vicenti, R.; Macciocca, M.; Pasquinelli, G.; Lima, M.; Parazza, I.; Magnani, V.; Venturoli, S. // Obstetrics & Gynecology International;2012, p1 

    Cancer treatments improve the survival rate of children and adolescents; however chemo- and radiotherapy result in gonadal damage leading to acute ovarian failure and sterility. Ovarian tissue cryopreservation allows long-term storage of primordial follicles and represents the only possibility...

  • Reference gene selection for real-time quantitative PCR analysis on ovarian cryopreservation by vitrification in mice. Yuanyuan, Shan; Qin, Su; Rongrong, Xu; Yujing, Gao; Chengbin, Pei; Jianjun, Ma; Yanzhou, Yang; Xiuying, Pei // Journal of Assisted Reproduction & Genetics;Aug2015, Vol. 32 Issue 8, p1277 

    Purpose: To ensure the correct interpretation of the results of quantitative real-time reverse transcription-polymerase chain reaction (qRT-PCR) from ovarian tissue cryopreserved by vitrification, it is critical to normalize expression levels to a reference gene with stable messenger RNA (mRNA)...

  • Evaluation of follicular genes pattern and growth of preantral follicles after culture in alginate hydrogel following vitrification of the mouse ovarian tissue. Asgari F.; Valojerdi M. R.; Ebrahimi B. // Iranian Journal of Reproductive Medicine;Apr2015 Supplement, p73 

    Introduction: This study was set up to evaluate the effect of ovarian tissue vitrification on the in vitro growth and pattern of follicular genes expression in mouse preantral follicles encapsulated within alginate hydrogel. Materials and Methods: Ovaries of 12-14 days old female NMRI mice...

  • Immature Cryopreserved Ovary Restores Puberty and Fertility in Mice without Alteration of Epigenetic Marks. Sauvat, Frédé rique; Capito, Carmen; Sarnacki, Sabine; Poirot, Catherine; Bachelot, Anne; Meduri, Geri; Dandolo, Luisa; Binart, Nadine // PLoS ONE;2008, Vol. 3 Issue 4, p1 

    Background: Progress in oncology could improve survival rate in children, but would probably lead to impaired fertility and puberty. In pre-pubertal girls, the only therapeutic option is the cryopreservation of one ovary. Three births have been reported after reimplantation of cryopreserved...

  • Freezing ovary tissue may help cancer patients preserve fertility. Law, Catherine // JNCI: Journal of the National Cancer Institute;09/04/96, Vol. 88 Issue 17, p1184 

    Focuses on the procedure called ovary cryopreservation which may be the next standard technique in fertility preservation. Usefulness for children and young women who are diagnosed with cancer and must undergo treatments; Clinical trial established by Genetics and the IVF Institute for...

  • Intact Human Ovary Successfully Frozen and Thawed.  // Fertility Weekly;11/22/2004, p7 

    The article cites a study regarding an intact human ovary. It states that an intact ovary with its vascular pedicule has been cryopreserved with resulting high survival rates by researchers in Belgium who used a passive cooling device. The article reveals that intact frozen-thawed ovaries have...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics