TITLE

Psychogenic nonepileptic seizures: a treatment review. What have we learned since the beginning of the millennium?

AUTHOR(S)
Baslet, Gaston
PUB. DATE
December 2012
SOURCE
Neuropsychiatric Disease & Treatment;2012 Part 2, Vol. 8, p585
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Psychogenic nonepileptic seizures (PNES) can significantly affect an individual's quality of life, the health care system, and even society. The first decade of the new millennium has seen renewed interest in this condition, but etiological understanding and evidence-based treatment availability remain limited. After the diagnosis of PNES is established, the first therapeutic step includes a presentation of the diagnosis that facilitates engagement in treatment. The purpose of this review is to present the current evidence of treatments for PNES published since the year 2000 and to discuss further needs for clinical treatment implementation and research. This article reviews clinical trials that have evaluated the efficacy of structured, standardized psychotherapeutic and psychopharmacological interventions. The primary outcome measure in clinical trials for PNES is event frequency, although it is questionable whether this is the most accurate indicator of functional recovery. Cognitive behavioral therapy has evidence of efficacy, including one pilot randomized, controlled trial where cognitive behavioral therapy was compared with standard medical care. The antidepressant sertraline did not show a significant difference in event frequency change when compared to placebo in a pilot randomized, double-blind, controlled trial, but it did show a significant pre- versus posttreatment decrease in the active arm. Other interventions that have shown efficacy in uncontrolled trials include augmented psychodynamic interpersonal psychotherapy, group psychodynamic psychotherapy, group psychoeducation, and the antidepressant venlafaxine. Larger clinical trials of these promising treatments are necessary, while other psychotherapeutic interventions such as hypnotherapy, mindfulness-based therapies, and eye movement desensitization and reprocessing may deserve exploration. Flexible delivery of treatment that considers the heterogeneous backgrounds of patients is emphasized as necessary for successful outcomes in clinical practice.
ACCESSION #
84699358

 

Related Articles

  • Multicenter Pilot Treatment Trial for Psychogenic Nonepileptic Seizures. LaFrance Jr, W. Curt; Baird, Grayson L.; Barry, John J.; Blum, Andrews.; Webb, Anne Frank; Keitner, Gabor I.; Machan, Jason T.; Miller, Ivan; Szaflarski, Jerzy P. // JAMA Psychiatry;Sep2014, Vol. 71 Issue 9, p997 

    IMPORTANCE There is a paucity of controlled treatment trials for the treatment of conversion disorder, seizures type, also known as psychogenic nonepileptic seizures (PNES). Psychogenic nonepileptic seizures, the most common conversion disorder, are as disabling as epilepsy and are not...

  • Health Matters. Whitaker, Phil // New Statesman;11/14/2014, Vol. 143 Issue 5236, p63 

    The author, a physician, discusses his effort to diagnose an elderly patient having seizure-like episodes where epilepsy had previously been ruled out. He says he made a diagnosis of pseudoseizures, or non-epileptic attack disorder (NEAD), a form of conversion illness based in emotional distress...

  • Treating Psychogenic Nonepileptic Seizures-- What Is the Best Strategy? Stong, Colby // Neurology Reviews;Mar2013, Vol. 21 Issue 3, p17 

    The article focuses on a research presented at the 66th Annual Meeting of the American Epilepsy Society on benefits of scripted psychiatry consultation to cure non-epileptic seizures and help patients improve their quality of life.

  • The Impact of PNES is About More than Counting Events. Dworetzky, Barbara // Epilepsy Currents;Sep/Oct2016, Vol. 16 Issue 5, p314 

    No abstract available.

  • Group Educational Therapy Helps Psychogenic Seizure Patients. Otto, M. Alexander // Neurology Reviews;Jan2013, Vol. 21 Issue 1, p9 

    The article presents reports that counseling and group therapy sessions will be more effective for the patients diagnosed with psychogenic nonepileptic seizures. It focuses on Professor Atul Maheshwari who said that team approach with a neurologist and psychiatrist gives the best outcomes for...

  • Core outcome domains for clinical trials in non-specific low back pain. Chiarotto, Alessandro; Deyo, Richard; Terwee, Caroline; Boers, Maarten; Buchbinder, Rachelle; Corbin, Terry; Costa, Leonardo; Foster, Nadine; Grotle, Margreth; Koes, Bart; Kovacs, Francisco; Lin, Chung-Wei; Maher, Chris; Pearson, Adam; Peul, Wilco; Schoene, Mark; Turk, Dennis; Tulder, Maurits; Ostelo, Raymond // European Spine Journal;Jun2015, Vol. 24 Issue 6, p1127 

    Purpose: Inconsistent reporting of outcomes in clinical trials of patients with non-specific low back pain (NSLBP) hinders comparison of findings and the reliability of systematic reviews. A core outcome set (COS) can address this issue as it defines a minimum set of outcomes that should be...

  • EVALUATION OF PATIENT REPORTED OUTCOME MEASURES IN ASSOCIATION WITH ANKYLOSING SPONDYLITIS RESPONSE TO TNFI: PRELIMINARY RESULTS FROM THE BIOEFFICACYSPA CLINICAL TRIAL. Gomes, João Lagoas; Lopes, Carina; Marona, José; Bernardes, Miguel; Pinto, P.; Santos, Helena; Tavares-Costa, José; Dias, João Madruga; Bernardo, Alexandra; Maia, Sara; Branco, Jaime C.; Pimentel-Santos, Fernando // Acta Reumatológica Portuguesa;2019 Special Issue, p30 

    Background: Patients reported outcome measures (PROMs) are routinely applied to patients with Ankylosing Spondylitis (AS) to improve disease management. TNFi have shown to be effective in improving quality of life and function in AS, but which PROMs better correlate with disease activity scores...

  • Measuring health outcomes of adolescents: report from a pilot study. Oluboyede, Yemi; Tubeuf, Sandy; McCabe, Chris // European Journal of Health Economics;Feb2013, Vol. 14 Issue 1, p11 

    There is a need to understand the practicality, validity and reliability of using utility measures with children and adolescents. We designed a pilot study in order to help guide the selection of an appropriate health-related quality-of-life (HRQoL) questionnaire for adolescents to be used in...

  • Effects of Family-Centered Empowerment Model Based Education Program on Quality of Life in Methamphetamine Users and Their Families. Ghasemi, Afsaneh; Foroshani, Abbass Rahimi; Kheibar, Nasrin; Latifi, Marziye; Khanjani, Narges; Afkari, Mohammad Eshagh; Taghdisi, Mohammad Hossein; Ghasemi, Faranak; Shojaeizadeh, Davoud; Dastoorpour, Maryam // Iranian Red Crescent Medical Journal;Mar2014, Vol. 16 Issue 3, p1 

    Background: Nowadays there are more concerns about drug treatment of methamphetamine abusers whereas quality of life (QOL) related supportive psychotherapy is less credited. Objectives: This study aimed to evaluate the effects of family-centered empowerment model on social support and QOL of...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics