The Phytochemical Screening And the Anti-Ulcer Activity of Methanolic Extract of Ixora coccinea Linn Leaf

Vetriselvan, S.; Eugine Felix, A.; Magendran, R.; Ponnaiyakannan, S.; Prabakaran, T.; Jothi, Shankar; Davan, Revathy
June 2012
Journal of Pharmacy Research;2012, Vol. 5 Issue 6, p3074
Academic Journal
The present study was conducted to study the phytochemicals and evaluate the antiulcer activity of extracts of leaf extract of Ixora Coccinea Linn. The extract at different doses used showed good anti ulcer activity which has been done significantly. These results were also comparable to Famotidine, the reference drugs used in this study. The overall experimental results suggests that the biologically active phytoconstituents such as flavonoids and glycosides present in the methanolic extract of plant Ixora Coccinea Linn, may be responsible for the significant antiulcer activity. Therefore, results justify the use of Ixora coccinea Linn as an antiulcer agent.


Related Articles

  • SCREENING OF ANTI ULCER ACTIVITY OF POLYHERBAL METANOLIC EXTRACTION IN RATS. Venkateswararao, Chitta; Venkataramana, K.; Rajesham, V. V. // Advances in Pharmacology & Toxicology;2014, Vol. 15 Issue 1, p49 

    The antiulcer activity of the poly herbal formulation (composed of the extracts from Terminalia chebula, tinospora cordifolia, Phyllanthus emblica, Portulaca oleracea) was evaluated in Pylorus ligation induced ulcer model in rats, Stress induced ulcer model in rats, Aspirin induced ulcer model...

  • Anti-Ulcer (Ulcer-Preventive) Activity of Ficus arnottiana Miq. (Moraceae) Leaf Methanolic Extract. Gregory, Marslin; Vithalrao, K. P.; Franklin, G.; Kalaichelavan, V. // American Journal of Pharmacology & Toxicology;2009, Vol. 4 Issue 3, p89 

    Problem statement: In spite of being one of the well-known medicinal plants used in Indian traditional medicine to treat several ailments, studies pertaining to the pharmacological properties of Ficus arnottiana are very scarce. We studied the anti-ulcer activity and acute toxicity of Ficus...

  • Phytochemical Investigation of Methanolic Extract of the Leaves of Pergularia daemia. Karthishwaran, K.; Mirunalini, S.; Dhamodharan, G.; Krishnaveni, M.; Arulmozhi, V. // Journal of Biological Sciences;2010, Vol. 10 Issue 3, p242 

    The present study deals with the phytochemical examination of therapeutic importance of Pergularia daemia, an important medicinal plant. Medicinal plants are as source of great economic value in the Indian subcontinent and continue to provide valuable therapeutic agents. This study involves the...

  • Abrus precatorius L. : A medicinal plant with potential as antibacterial agent. De Britto, A. John; Rathna Kumar, P. Benjamin Jeya; Sheeba Gracelin, D. Herin // Journal of Pharmacy Research;2012, Vol. 5 Issue 2, p1207 

    Abrus precatorius L. is a medicinal plant. The medicinal properties of the plants are determined by the presence of secondary metabolites (phytochemical constituents) in it. In the present study the phytochemical analysis and antibacterial activity in the methanol extract of five parts (leaves,...

  • TO ESTABLISH THE ULCEROGENIC POTENTIAL IF ANY, OF GINGER-JUICE ZINGIBER OFFICINALE ROSCOE (ZINGIBERACEAE) ON IMPORTANT PARAMETERS OF GASTRIC ULCERATION. Prasad, S. S.; Sinha, Anita; Patel, Kamlesh; Dumatar, Chandresh; Vajpeyee, S. K.; Bhavsar, V. H. // International Journal of Pharmaceutical Sciences & Research;Nov2012, Vol. 3 Issue 11, p4472 

    The aim of this study was to investigate the possibility of gastric-ulceration by ginger-juice (Zingiber officinale Roscoe) in rat. (A) Albino rats (n=6-12) were administered G.J at two doses (2ml & 4 ml/rat, p.o) as single administration and chronic treatment over period of 30 days. Following...

  • Pharmacognostical standardization of leaves of Ixora coccinea, linn. Vadivu, R.; Jayshree, N.; Kasthuri, C.; Rubhini, K.; Rukmankathan, G. // Journal of Pharmaceutical Sciences & Research;2010, Vol. 2 Issue 3, p164 

    Ixora coccinea Linn. is traditionally found to be useful for many ailments like hepatoprotective, Chemoprotective , antimicrobial, anti oxidant , antinociceptive and anti - inflammatory activities. The present study highlights the botanical as well as phytochemical studies including parameters...

  • Investigation of Phytochemical and Antioxidant Properties of Methanol Extract and Fractions of Ballota limbata (Lamiaceae). WAHEED, I.; AHMAD, M.; SYED, N.-H.; ASHRAF, ROMEEZA // Indian Journal of Pharmaceutical Sciences;May/Jun2014, Vol. 76 Issue 3, p251 

    Ballota limbata (Lamiaceae) has been used for its antispasmodic, antiulcer, diuretic, vermifuge and sedative effects in folk medicine. However, little is known about how does it work to produce these therapeutic actions. Present research investigated phytochemical components and antioxidant...

  • Antiulcer activity of aqueous extract of Musa paradisiaca. Bhatnagar, Surabhi; Garg, Vipin K.; Sharma, Pramod K.; Jain, Swati // Der Pharmacia Sinica;2011, Vol. 2 Issue 4, p40 

    Musa paradisiaca (Family: Musaceae) is a perennial tree like herb. The aqueous extract of leaves of Musa paradisiaca was prepared by hot maceration and then it was subjected to priliminary phytochemical investigation.Then antiulcer efficacy of aqueous extract of leaves of Musa paradisiaca at 250...

  • Anti-ulcer activity of Bombax buonopozense P. Beauv. aqueous leaf extract (Fam: Bombacaceae). Nwagba, C. A.; Ezugwu, C. O.; Eze, C. C.; Anowi, F. C.; Ezea, S. C.; Nwakile, C. D. // Journal of Applied Pharmaceutical Science;Feb2013, Vol. 3 Issue 2, p139 

    The objective of this study was to investigate the anti-ulcer activity of leaves of Bombax buonopozense P. Beauv. (Bombacaceae) in rats. Fresh dried leaves of B.buonopozense were extracted by cold maceration which yielded a mucilaginuous aqueous extract. Anti-ulcer effects of the aqueous extract...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics