The Short to Medium-Term Risks of Intracameral Phenylephrine

Williams, Gwyn S.; Radwan, Mahmoud; Kadare, Shwan; Williams, Christopher P. R.
October 2012
Middle East African Journal of Ophthalmology;Oct-Dec2012, Vol. 19 Issue 4, p357
Academic Journal
Purpose: To compare outcomes and complications of patients undergoing phacoemulsification with and without the administration of intracameral phenylephrine. Materials and Methods: In this retrospective study, a chart review was performed. Two groups with an equal number of patients who did or did not receive intracameral phenylephrine during phacoemulsification were compared for differences in outcomes, risk factors and complications. The Chi-square test was used for comparison between groups. P<0.05 was statistically significant. Results: The two groups were well matched with regard to preoperative ophthalmic and systemic risk factors for complications and had very similar phacoemulsification power and time profiles. No differences in outcome were detected (P>0.05, all comparisons). Conclusion: This retrospective study suggests that intracameral phenylephrine normalizes the intraoperative risk of small pupil cataract surgery and is not associated with an increased risk of systemic or postoperative ophthalmic complications.


Related Articles

  • Outcomes After Liver Transplant in Patients Aged 70 Years or Older Compared With Those Younger Than 60 Years. Aduen, Javier F.; Sujay, Bangarulingam; Dickson, Rolland C.; Heckman, Michael G.; Hewitt, Winston R.; Stapelfeldt, Wolf H.; Steers, Jeffrey L.; Harnois, Denise M.; Kramer, David J. // Mayo Clinic Proceedings;Nov2009, Vol. 84 Issue 11, p973 

    OBJECTIVE: To compare mortality, graft loss, and postoperative complications after liver transplant in older patients (≥70 years) with those in younger patients (<60 years). PATIENTS AND METHODS: Outcomes for 42 patients aged 70 years or older who underwent liver transplant were compared...

  • Adherence to Biochemical Monitoring Recommendations in Patients Starting with Renin Angiotensin System Inhibitors: A Retrospective Cohort Study in the Netherlands. Bootsma, Janet E. M.; Wane-van Herwaarden, Margreet F.; Verbeek, André L. M.; Füssenich, Peter; de Smet, Peter A. G. M.; Olde Rikkert, Marcel G.; Kramers1, Cornelis // Drug Safety;2011, Vol. 34 Issue 7, p605 

    Background: Renin angiotensin system inhibitors (RASIs) are frequently involved in serious adverse events. These events principally occur in high-risk patients and often arise within the first days after treatment initiation; therefore, guidelines recommend biochemical monitoring within 3 weeks...

  • Phenylephrine.  // Reactions Weekly;Nov2014, Vol. 1528 Issue 1, p170 

    The article presents a case study of a 59-year-old woman who developed reversible cerebral vasoconstriction syndrome (RCVS) leading to intracerebral haemorrhage (ICH) during treatment with phenylephrine.

  • Phenylephrine/tropicamide.  // Reactions Weekly;1/8/2011, Issue 1333, p30 

    This article describes a case study of two neonates who developed vasoconstriction of periorbital skin vessels following application of phenylephrine/tropicamide eye drops prior to eye examination.

  • Outcome Comparison Among Laparoscopic Duhamel, Laparotomic Duhamel, and Transanal Endorectal Pull-Through: A Single-Center, 18-Year Experience. Giuliani, Stefano; Betalli, Pietro; Narciso, Alessandra; Grandi, Francesca; Midrio, Paola; Mognato, Guendalina; Gamba, Piergiorgio // Journal of Laparoendoscopic & Advanced Surgical Techniques;Nov2011, Vol. 21 Issue 9, p859 

    Purpose: Transanal endorectal pull-through has changed the treatment of Hirschsprung's disease (HD) in the past decade. The aim of the study was to compare outcomes, obtained in a single center, with laparotomic Duhamel (LTD), laparoscopic Duhamel (LSD), and laparoscopic-assisted transanal...

  • Risks of complications by attending physicians after performing nighttime procedures. Chaudhury, Prosanto K.; Warnock, Garth L.; Whalen, Thomas V. // Canadian Journal of Surgery;Oct2012, Vol. 55 Issue 5, p337 

    Objective: To determine whether sleep opportunities for attending surgeons and obstetricians/gynecologists are associated with the risk of complications. Design: Matched retrospective cohort study of procedures performed from 1999 to 2008 by attending physicians (86 surgeons, 134...

  • Complications of kidney transplantation with grafts from expanded criteria donors. Barba, Javier; Zudaire, Juan; Robles, José; Rosell, David; Berian, José; Pascual, Ignacio // World Journal of Urology;Aug2013, Vol. 31 Issue 4, p893 

    Purpose: The limited availability of kidneys for transplantation has been addressed by expanding the criteria for allowing a donor kidney to be transplanted, but this tendency may cause suboptimal kidneys to be implanted and could be associated with greater risk of complications. Methods: A...

  • The Abandoned Radical Hysterectomy for Cervical Cancer: Clinical Predictors and Outcomes. Gray, Heidi J.; Seifert, Erin; Saly Rosas, Victor G.; Nicandri, Katrina F.; Wui-Jin Koh; Goff, Barbara A. // Obstetrics & Gynecology International;2010, Vol. 2010, p1 

    Objective. Cervical cancer patients who had an abandoned radical hysterectomy were evaluated for preoperative clinical predictors, complication rates, and outcomes. Study Design. IRB approval was obtained for this retrospective analysis and chart review was performed. Results. From 268 women...

  • Ephedrine/phenylephrine.  // Reactions Weekly;10/15/2011, Issue 1373, p14 

    The article describes the case of a 37-year-old woman who developed hypertension and vasospasm, resulting to a coronary artery dissection after administration of phenylephrine and ephedrine during a caesarean section.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics