Norovirus Immunity and the Great Escape

Debbink, Kari; Lindesmith, Lisa C.; Donaldson, Eric F.; Baric, Ralph S.
October 2012
PLoS Pathogens;Oct2012, Vol. 8 Issue 10, Special section p1
Academic Journal
The article focuses on the evolution and structure of norovirus (NoV), its interaction with the host, immune response and development of therapies against it. NoV is a member of the Calicivirus family that cause food-borne viral gastroenteritis in humans and genetically evolve in the gastrointestinal system. The defense against NoV include vaccination, monoclonal antibodies and the natural immune response of CD4+ T cells.


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