TITLE

Granulation Tissue and Granuloma: Two terms with very different meanings

AUTHOR(S)
CONSOLARO, Alberto; LEAHY, Franklin Moreira
PUB. DATE
October 2011
SOURCE
Revista Dental Press de Periodontia e Implantologia;oct-dec2011, Vol. 5 Issue 4, p16
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The conceptual confusion and the equivocal microscope diagnosis are common when using the terms granulation tissue and granuloma. When the damaged area is free of agressor agent, the granulation tissue, a tissue that is almost embryonic, is formed in that site in order to enable the formation of a new connective tissue, therefore, reestablishing the normality and/or filling the spaces. On the other hand, the offender persistence promotes the persistence of inflammation with macrophages and derived cells circumscribing them, limiting their aggressiveness. Such macrophage agglomeration around the persistent offender is named granuloma, which is a synonym of chronic inflammation. Although they sound similar, the terms granuloma and granulation tissue represent different phenomena and should not be used as synonyms in microscopic analysis, as they may induce equivocal interpretation.
ACCESSION #
83239500

 

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