TITLE

A new paradigm in viral resistance

AUTHOR(S)
Ruiz, Autumn; Russell, Stephen J
PUB. DATE
November 2012
SOURCE
Cell Research;Nov2012, Vol. 22 Issue 11, p1515
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The rapid mutation of RNA viruses allows for the acquisition of resistance to drugs directly targeting viral proteins. Therefore, a novel approach to the development of antivirals centers on targeting host factors critical to viral replication. A recent report has brought to light the potential for RNA viruses to also develop resistance against compounds targeting crucial host factors, suggesting that a combination of drugs with various targets may be necessary for preventing resistance.
ACCESSION #
83183840

 

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