TITLE

Hyperkalaemia in the age of aldosterone antagonism

AUTHOR(S)
Chapagain, A.; Ashman, N.
PUB. DATE
November 2012
SOURCE
QJM: An International Journal of Medicine;Nov2012, Vol. 105 Issue 11, p1049
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Hyperkalaemia is well recognized as a medical emergency. However, with the publication of trials showing benefit with renin-aldosterone axis suppression in heart failure, the epidemiology of patients presenting with hyperkalaemia has changed. The reported incidence of rate of serious hyperkalaemia (>6.0 mEq/l of potassium) ranges from 6 to 12% in patients on spironolactone with congestive cardiac failure (CCF). A rational choice of therapy based on present evidence is different from the traditionally used algorithm, given our understanding of the physiology relevant to this patient group. This article discusses the changing face of hyperkalaemia and the present evidence and discusses options in treatment of hyperkalaemia.
ACCESSION #
82975379

 

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