NLRC4: panic button for the calm intestinal phagocyte

November 2012
Mucosal Immunology (1933-0219);Nov2012, Vol. 5 Issue 6, p594
Academic Journal
The article focuses on the aspects of intestinal phagocytes, which are said to be equipped with the inflammasome-mediated production of interleukin (IL)-1β. It says that the use of IL-1β is limited by tight control. It states that the activation of inflammasome requires recognition of various microbial components. It adds that intestinal phagocytes can activate NLRC4 to change host defense.


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