TITLE

Vitamin D impact on immune functions: implications for preventive strategy of allergic disease?

AUTHOR(S)
Szczawińska-Popłonyk, Aleksandra; Bręborowicz, Anna
PUB. DATE
May 2012
SOURCE
Advances in Dermatology & Allergology / Postepy Dermatologii i A;2012, Vol. 29 Issue 3, p176
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Asthma and allergic diseases are substantial global health problems with a higher prevalence in the westernized countries. It has been proposed that vitamin D deficiency resulting from reduced exposure to sunlight and changes in lifestyle as well as dietary habits may contribute to a high prevalence of asthma and allergic diseases. This review examines the scientific evidence for pluripotent immunoregulatory actions of vitamin D in conjunction with nuclear actions as well as genetic and epigenetic determinants of the vitamin D effects. Findings of epidemiological and clinical studies on the potential association between vitamin D and allergic disease and asthma are reviewed.
ACCESSION #
82544305

 

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