Frecuencia de leucemias agudas

González-Salas, Wendy Marlene; Olarte-Carrillo, Irma; Gutiérrez-Romero, Mario; Montaño-Figueroa, Efreen Horacio; Martínez-Murillo, Carlos; Ramos-Peñafiel, Christian Omar
March 2012
Revista Medica del IMSS;2012, Vol. 50 Issue 2, p167
Academic Journal
Objective: to compare the frequency of acute leukemia in two periods of study in a reference Hospital at Mexico City. Methods: it was an observational study. There were registered 250 cases with the morphology diagnostic criterion of acute leukemia. Results: 63 cases versus 92 of acute lymphoid leukemia (ALL) and 16 versus 79 acute myeloid leukemia (AML) of 1990-1992 versus 2008-2009 respectively was observed; corresponding to 62 % in total of ALL in both periods and 38 % of AML. The ALL was the most frequent variant (62 % versus 38 %). The median age was 26 years, male 52 %. It showed a significant increase in the number of admissions in the period of 2008-2009 and acute promyelocytic leukemia also showed an increase (p = 0.001). Conclusions: acute leukemia is the main cause of admission, mortality and morbidity. Our study differs slightly from the literature; the leukemia that diagnostic with major frequency was the acute lymphoid leukemia increasing his number in the period of 2008-2009. The significant rise due to an increase use of new diagnostic tools such as the flow cytometry and molecular biology.


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