TITLE

Solid lipid nanoparticles modified with stearic acid-octaarginine for oral administration of insulin

AUTHOR(S)
Zhen-Hai Zhang; Yin-Long Zhang; Jian-Ping Zhou; Hui-Xia Lv
PUB. DATE
January 2012
SOURCE
International Journal of Nanomedicine;2012, Vol. 7, p3333
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
No abstract available.
ACCESSION #
82509060

 

Related Articles

  • FLURBIPROFEN LOADED SOLID LIPID NANOPARTICLES, FORMULATION AND OPTIMIZATION BY USING RESPONSE SURFACE METHODOLOGY. BHATTACHARYYA, SUBHRA PRAKASH; GHOSHAL, INGANA; BHATTACHARYYA, INDRANI; DASGUPTA, SANDIPAN; MAZUMDER, BHASKAR // International Journal of Pharmacy & Pharmaceutical Sciences;Dec2012 Supplement 5, Vol. 4, p103 

    Flurbiprofen loaded solid lipid nanoparticles, formulation and optimization by using response surface methodology. The formulation of drugs as nanocrystal has rapidly evolved into a mature drug delivery strategy. The major characteristic of these systems is the rapid dissolution velocity,...

  • Peptide-Loaded Solid Lipid Nanoparticles Prepared through Coacervation Technique. Gallarate, Marina; Battaglia, Luigi; Peira, E.; Trotta, Michele // International Journal of Chemical Engineering (1687806X);2011, p1 

    Stearic acid solid lipid nanoparticles were prepared according to a new technique, called coacervation. The main goal of this experimental work was the entrapment of peptide drugs into SLN, which is a difficult task, since their chemical characteristics (molecular weight, hydrophilicity, and...

  • Cavinton -- Loaded Solid Lipid Nanoparticles: Design and Characterization. Laxman Mhetre, Raksha; Bhanudas Hol, Vishal; Narayan Bajaj, Amrita; Jadhav, Ram // International Journal of Pharmaceutical & Phytopharmacological R; 

    Solid lipid nanoparticles (SLNs) are novel colloidal particles for oral delivery with enhanced absorption rate. They overcome the disadvantages of other colloidal carriers such as emulsion, liposome, and polymeric nanoparticles. Cavinton is unique memory enhancer drug with short half-life and...

  • Lipid nanoceuticals: Current status and future perspective. Narang, Jasjeet Kaur // International Journal of Pharmaceutical Investigation;Jul-Sep2014, Vol. 4 Issue 3, p107 

    The author discusses the application of drugs through lipid-based nanoformulations in answer to the challenges faced by administration via oral route. The shortcomings of lipid-based nanoceuticals such as poor drug loading and toxicity are mentioned. The formulation, application, and advantages...

  • Solid lipid Nanoparticles for Oral delivery of Poorly Soluble Drugs. Jawahar, N.; Meyyanathan, S. N.; Reddy, Gowtham; Sood, Sumeet // Journal of Pharmaceutical Sciences & Research;2012, Vol. 4 Issue 7, p1848 

    Solid Lipid nanoparticles show interesting features concerning therapeutic purposes. Their main characteristic is the fact that they are prepared with physiologically well-tolerated lipids. Different substances have been entrapped into lipid Nano-particles, ranging from lipophilic and...

  • Characterization of Carbamazepine-Loaded Solid Lipid Nanoparticles Prepared by Rapid Expansion of Supercritical Solution. Akbari, Zahra; Amanlou, Massoud; Karimi-Sabet, Javad; Golestani, Abolfazl; Niasar, Mojtaba Shariaty // Tropical Journal of Pharmaceutical Research;Dec2014, Vol. 13 Issue 12, p1955 

    Purpose: To prepare carbamazepine-loaded solid lipid nanoparticles (CBZ-SLN) for prolonged release of CBZ in oral drug delivery. Methods: CBZ-loaded SLNs were prepared by rapid expansion of supercritical solution (RESS). SLNs were formulated using stearic acid as the lipid component. Initially,...

  • Therapeutic Nanosystems for Oral Administration of Insulin. do Carmo, Flavia A.; Sathler, Plinio C.; Zancan, Patricia; Rodrigues, Carlos R.; Castro, Helena C.; de Sousa, Valeria P.; Sola-Penna, Mauro; Cabral, Lucio M. // Current Pharmaceutical Biotechnology;Jul2014, Vol. 15 Issue 7, p620 

    The treatment of Diabetes Mellitus (DM), a chronic disease, is primarily based upon administration of insulin forms to patients. Conventional subcutaneous administration is associated with a large number of complications, therefore, several new strategies have been developed. Amongst these...

  • Paromomycin loaded solid lipid nanoparticles: Characterization of production parameters. Ghadiri, Maryam; Vatanara, Alireza; Doroud, Delaram; Roholamini Najafabadi, A. // Biotechnology & Bioprocess Engineering;Jun2011, Vol. 16 Issue 3, p617 

    Paromomycin has been shown to have anti-leishmaniasis activity; however, its clinical use is restricted to some content owing to its poor skin penetration. To identify innovative methods of dermal administration of paromomycin and controlling the release delivery system, paromomycin was loaded...

  • Nanoparticle based insulin delivery system: the next generation efficient therapy for Type 1 diabetes. Sharma, Garima; Sharma, Ashish Ranjan; Ju-Suk Nam; Doss, George Priya C.; Sang-Soo Lee; Chakraborty, Chiranjib // Journal of Nanobiotechnology;10/24/2015, Vol. 13, p1 

    Diabetic cases have increased rapidly in recent years throughout the world. Currently, for type-1 diabetes mellitus (T1DM), multiple daily insulin (MDI) injections is the most popular treatment throughout the world. At this juncture, researchers are trying to develop different insulin delivery...

  • DESIGN AND EVALUATION OF SOLID LIPID NANOPARTICLES OF TAMOXIFEN CITRATE BY FACTORIAL DESIGN. Basu, B.; Dharamsi, A. // Pharma Science Monitor;Jul2012, Vol. 3 Issue 3, p134 

    In this study Solid Lipid Nanoparticles (SLNs) containing Tamoxifen citrate, nonsteroidalantiestrogens have been loaded by full factorial design and to be used as breast cancer therapy, were prepared by hot High Pressure Homogenization techniques. A 32 factorial design was utilized to optimize...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics