Development of 3D in vitro platform technology to engineer mesenchymal stem cells

Hosseinkhani, Hossein; Po-Da Hong; Dah-Shyong Yu; Yi-Ru Chen; Ickowicz, Diana; Farber, Ira-Yudovin; Domb, Abraham J.
January 2012
International Journal of Nanomedicine;2012, Vol. 7, p3035
Academic Journal
No abstract available.


Related Articles

  • Stem Cell Research: Past, Present, and Future. Lindeque, Bennie G.P. // Orthopedics;May2006, Vol. 29 Issue 5, p392 

    Discusses technological innovations and developments in stem cell research. Effects of the complexity of tissue engineering on the ability to apply stem cell technology; Overview of the ability of mesenchymal stem cells to differentiate into neurons and glia in mice; Future plans for stem cell...

  • Human iPSC-Derived Miniature Organs: A Tool for Drug Studies. Takebe, T; Taniguchi, H // Clinical Pharmacology & Therapeutics;Sep2014, Vol. 96 Issue 3, p310 

    In vitro organogenesis is now becoming a realistic goal of stem cell biology, as one can obtain an unlimited number of pluripotent stem cells through reprogramming technology. One practical challenge is to develop a four-dimensional (4-D) stem cell culture system whereby multiple progenitors...

  • Fabrication of Biomimetic Bone Tissue Using Mesenchymal Stem Cell-Derived Three-Dimensional Constructs Incorporating Endothelial Cells. Sasaki, Jun-Ichi; Hashimoto, Masanori; Yamaguchi, Satoshi; Itoh, Yoshihiro; Yoshimoto, Itsumi; Matsumoto, Takuya; Imazato, Satoshi // PLoS ONE;Jun2015, Vol. 10 Issue 6, p1 

    The development of technologies to promote vascularization of engineered tissue would drive major developments in tissue engineering and regenerative medicine. Recently, we succeeded in fabricating three-dimensional (3D) cell constructs composed of mesenchymal stem cells (MSCs). However, the...

  • Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep. Liechty, Kenneth W.; MacKenzie, Tippi C.; Shaaban, Aimen F.; Radu, Antoneta; Moseley, AnneMarie B.; Deans, Robert; Marshak, Daniel R.; Flake, Alan W. // Nature Medicine;Nov2000, Vol. 6 Issue 11, p1282 

    Mesenchymal stem cells are multipotent cells that can be isolated from adult bone marrow and can be induced in vitro and in vivo to differentiate into a variety of mesenchymal tissues, including bone, cartilage, tendon, fat, bone marrow stroma, and muscle. Despite their potential clinical...

  • New Developments and Trends in Tissue Engineering: An Update. Horch, Raymund E. // Journal of Tissue Science & Engineering;2012, Vol. 3 Issue 1, Special section p1 

    The author discusses developments and trends related to tissue engineering (TE). Interest in mesenchymal stem cells (MSC) for TE applications is said to have increased with the emergence of new technologies for handling adult mesenchymal or embryonic stem cells. Research indicates that a system...

  • A combinatorial cell-laden gel microarray for inducing osteogenic differentiation of human mesenchymal stem cells. Dolatshahi-Pirouz, Alireza; Nikkhah, Mehdi; Gaharwar, Akhilesh K.; Hashmi, Basma; Guermani, Enrico; Aliabadi, Hamed; Camci-Unal, Gulden; Ferrante, Thomas; Foss, Morten; Ingber, Donald E.; Khademhosseini, Ali // Scientific Reports;1/31/2014, p1 

    Development of three dimensional (3D) microenvironments that direct stem cell differentiation into functional cell types remains a major challenge in the field of regenerative medicine. Here, we describe a new platform to address this challenge by utilizing a robotic microarray spotter for...

  • Uniaxial cyclic strain of human adipose-derived mesenchymal stem cells and C2C12 myoblasts in coculture. Dugan, James M.; Cartmell, Sarah H.; Gough, Julie E. // Journal of Tissue Engineering;Jan-Dec2014, Vol. 5, p1 

    Tissue engineering skeletal muscle in vitro is of great importance for the production of tissue-like constructs for treating tissue loss due to traumatic injury or surgery. However, it is essential to find new sources of cells for muscle engineering as efficient in vitro expansion and culture of...

  • Fibroblasts derived from human embryonic stem cells direct development and repair of 3D human skin equivalents. Shamis, Yulia; Hewitt, Kyle J.; Carlson, Mark W.; Margvelashvilli, Mariam; Dong, Shumin; Kuo, Catherine K.; Daheron, Laurence; Egles, Christophe; Garlick, Jonathan A. // Stem Cell Research & Therapy;2011, Vol. 2 Issue 1, p1 

    Introduction: Pluripotent, human stem cells hold tremendous promise as a source of progenitor and terminally differentiated cells for application in future regenerative therapies. However, such therapies will be dependent upon the development of novel approaches that can best assess tissue...

  • SSEA-4 is a Marker of Human Deciduous Periodontal Ligament Stem Cells. Fukushima, H.; Kawanabe, N.; Murata, S.; Ishihara, Y.; Yanagita, T.; Balam, T.A.; Yamashiro, T. // Journal of Dental Research;Oct2012, Vol. 91 Issue 10, p955 

    Although human deciduous teeth are an ideal source of adult stem cells, no method for identifying deciduous periodontal ligament (D-PDL) stem cells has so far been developed. In the present study, we investigated whether stage-specific embryonic antigen (SSEA)-4 is a marker that could be used to...

  • Showcasing Mesoblast: The world leader in regenerative medicine products.  // Australasian Biotechnology;Mar2013, Vol. 23 Issue 1, p16 

    The article features the Australia-based regenerative medicine products supplier Mesoblast. Topics discussed include the company's Mesenchymal Precursor Cell (MPC) technology platform for diabetes treatment, its strategic alliance with Teva Pharmaceutical Industries Ltd. to develop stem cell...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics