TITLE

Design of cationic nanostructured heterolipid matrices for ocular delivery of methazolamide

AUTHOR(S)
Youshia, John; Kamel, Amany O.; Shamy, Abdelhameed El.; Mansour, Samar
PUB. DATE
January 2012
SOURCE
International Journal of Nanomedicine;2012, Vol. 7, p2483
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
No abstract available.
ACCESSION #
82508986

 

Related Articles

  • Pharmacodynamics of Piroxicam from Novel Solid Lipid Microparticles Formulated with Homolipids from Bos indicus. Nnamani, Petra O.; Attama, Anthony A.; Kenechukwu, Franklin C.; Ibezim, Emmanuel C.; Adikwu, Michael U. // Current Drug Delivery;Dec2013, Vol. 10 Issue 6, p645 

    The dissolution of piroxicam is a limiting step in its bioavailability on account of its hydrophobicity. The objective of this research was to formulate novel solid lipid microparticles (SLMs) based on homolipids (admixtures of tallow fat (TF) and Softisan ® 142 (SFT) templated with...

  • Cationic Polymer Optimization for Efficient Gene Delivery. Xiaoli Sun; Na Zhang // Mini Reviews in Medicinal Chemistry;Feb2010, Vol. 10 Issue 2, p108 

    The polyplexes which are formed between cationic polymers and DNA through electrostatic interactions and thus known as polycation/DNA complexes, are by far the most widely used non-viral gene delivery vectors. Many factors such as molecular weight, surface charge, charge density, hydrophilicity...

  • Ocular Biocompatibility and Structural Integrity of Micro- and Nanostructured Poly(caprolactone) Films. Bernards, Daniel A.; Bhisitkul, Robert B.; Wynn, Paula; Steedman, Mark R.; Lee, On-Tat; Wong, Fergus; Thoongsuwan, Somanus; Desai, Tejal A. // Journal of Ocular Pharmacology & Therapeutics;Mar2013, Vol. 29 Issue 2, p249 

    The identification of biomaterials that are well tolerated in the eye is important for the development of new ocular drug delivery devices and implants, and the application of micro- and nanoengineered devices to biomedical treatments is predicated on the long-term preservation within the target...

  • Translating Nanotechnology from Bench to Pharmaceutical Market: Barriers, Success, and Promises. Date, Abhijit A.; Patil, Rajesh R.; Panicucci, Riccardo; Souto, Eliana B.; Lee, Robert W. // Journal of Drug Delivery;2012, p1 

    An introduction is presented in which the editors discuss various studies within the issue on topics related to nanotechnologies, translation of nanotechnologies to pharmaceutical market and development of a cationic nanoemulsion Novasorb for ocular drug delivery system.

  • Episcleral, Intrascleral, and Suprachoroidal Routes of Ocular Drug Delivery - Recent Research Advances and Patents. Gilger, Brian C.; Mandal, Abhirup; Shah, Sujay; Mitra, Ashim K. // Recent Patents on Drug Delivery & Formulation;Aug2014, Vol. 8 Issue 2, p81 

    Subconjunctival/episcleral, intrascleral, and suprachoroidal routes of drug delivery for treatment of posterior segment eye diseases have become more feasible and popular in the past few years. These routes have the advantage of bypassing the main barriers to topical drug penetration, the ocular...

  • Lipid Nanoparticles as Drug/Gene Delivery Systems to the Retina. del Pozo-Rodríguez, Ana; Delgado, Diego; Gascón, Alicia R.; Solinís, Maria Ángeles // Journal of Ocular Pharmacology & Therapeutics;Mar2013, Vol. 29 Issue 2, p173 

    This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles, Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug/gene delivery systems for retinal diseases. Most drug products for ocular disease treatment are marketed as eye drop formulations...

  • Successfully Improving Ocular Drug Delivery Using the Cationic Nanoemulsion, Novasorb. Lallemand, Frederic; Daull, Philippe; Benita, Simon; Buggage, Ronald; Garrigue, Jean-Sebastien // Journal of Drug Delivery;2012, p1 

    Topical ophthalmic delivery of active ingredients can be achieved using cationic nanoemulsions. In the last decade, Novagali Pharma has successfully developed and marketed Novasorb, an advanced pharmaceutical technology for the treatment of ophthalmic diseases. This paper describes the main...

  • Manufacturing techniques and excipients used during the formulation of oil-in-water type nanosized emulsions for medical applications. Tamilvanan, Shunmugaperumal; Senthilkumar, Sudalaimuthu Ramachandran; baskar, Raj; Sekharan, Thenrajan Raja // Journal of Excipients & Food Chemicals;2010, Vol. 1 Issue 1, p11 

    Medically, the oil-in-water nanosized emulsions are used mainly as delivery carriers for lipophilic drug molecules which show therapeutic activity when administered via parenteral, ocular and transdermal routes. To extract multifunctional activities, the nanosized emulsions containing neutral,...

  • Novel Strategies for Anterior Segment Ocular Drug Delivery. Cholkar, Kishore; Patel, Sulabh P.; Vadlapudi, Aswani Dutt; Mitra, Ashim K. // Journal of Ocular Pharmacology & Therapeutics;Mar2013, Vol. 29 Issue 2, p106 

    Research advancements in pharmaceutical sciences have led to the development of new strategies in drug delivery to anterior segment. Designing a new delivery system that can efficiently target the diseased anterior ocular tissue, generate high drug levels, and maintain prolonged and effective...

  • Dendrimer Nanoparticles for Ocular Drug Delivery. Kambhampati, Siva P.; Kannan, Rangaramanujam M. // Journal of Ocular Pharmacology & Therapeutics;Mar2013, Vol. 29 Issue 2, p151 

    Eye is a unique organ of perfection and complexity, and is a microcosm of the body in many ways. It represents a great opportunity for nanomedicine, since it is readily accessible-allowing for direct drug/gene delivery to maximize the therapeutic effect and minimize side effects. The development...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics