TITLE

Co-encapsulation of magnetic Fe3O4 nanoparticles and doxorubicin into biodegradable PLGA nanocarriers for intratumoral drug delivery

AUTHOR(S)
Yanhui Jia; Mei Yuan; Huidong Yuan; Xinglu Huang; Xiang Sui; Xuemei Cui; Fangqiong Tang; Jiang Peng; Jiying Chen; Shibi Lu; Wenjing Xu; Li Zhang; Quanyi Guo
PUB. DATE
January 2012
SOURCE
International Journal of Nanomedicine;2012, Vol. 7, p1697
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
No abstract available.
ACCESSION #
82508920

 

Related Articles

  • Tailoring magnetic PLGA nanoparticles suitable for doxorubicin delivery. Tansık, Gülistan; Yakar, Arzu; Gündüz, Ufuk // Journal of Nanoparticle Research;Jan2014, Vol. 16 Issue 1, p1 

    One of the main problems of current cancer chemotherapy is the lack of selectivity of anti-cancer drugs to tumor cells, which leads to systemic toxicity and adverse side effects. In order to overcome these limitations, researches on controlled drug delivery systems have gained much attention....

  • Biodegradable thermoresponsive polymeric magnetic nanoparticles: a new drug delivery platform for doxorubicin. Andhariya, Nidhi; Chudasama, Bhupendra; Mehta, R.; Upadhyay, R. // Journal of Nanoparticle Research;Apr2011, Vol. 13 Issue 4, p1677 

    The use of nanoparticles as drug delivery systems for anticancer therapeutics has great potential to revolutionize the future of cancer therapy. The aim of this study is to construct a novel drug delivery platform comprising a magnetic core and biodegradable thermoresponsive shell of...

  • Biodegradable PLGA- b-PEG polymeric nanoparticles: synthesis, properties, and nanomedical applications as drug delivery system. Locatelli, Erica; Comes Franchini, Mauro // Journal of Nanoparticle Research;Dec2012, Vol. 14 Issue 12, p1 

    During the past decades many synthetic polymers have been studied for nanomedicine applications and in particular as drug delivery systems. For this purpose, polymers must be non-toxic, biodegradable, and biocompatible. Polylactic- co-glycolic acid (PLGA) is one of the most studied polymers due...

  • Synthesis of magnetic CoZnFeO-chitosan nanoparticles as ph responsive drug delivery system. Lian, Qi; Zheng, Xue-Fang; Wang, Da-Jiang // Russian Journal of General Chemistry;Jan2015, Vol. 85 Issue 1, p152 

    Chitosan magnetic nanoparticles can be used as drugs carriers. Unlike the traditional particles, the novel magnetic CoZnFeO-chitosan nanoparticles were highly biodegradable. Such nanoparticles with core-shell structure were prepared efficiently. Transmission and scanning electron microscopies...

  • Nanoparticles based on PLGA and its co-polymer: An overview. Muthu, M. S. // Asian Journal of Pharmaceutics (Medknow Publications & Media Pvt;2009, Vol. 3 Issue 4, p266 

    Poly (D, L-lactide-co-glycolide) (PLGA) is approved by the Food and Drug Administration for drug delivery use. The polymeric nanoparticles based on PLGA and its co-polymer are designed for controlled and targeted drug delivery. Also, PLGA and its co-polymer are important in designing...

  • Magnetic core-shell nanoparticles for drug delivery by nebulization. Kumar Verma, Navin; Crosbie-Staunton, Kieran; Satti, Amro; Gallagher, Shane; Ryan, Katie B.; Doody, Timothy; McAtamney, Colm; MacLoughlin, Ronan; Galvin, Paul; Burke, Conor S.; Volkov, Yuri; Gun'ko, Yurii K. // Journal of Nanobiotechnology;2013, Vol. 11 Issue 1, p1 

    Background: Aerosolized therapeutics hold great potential for effective treatment of various diseases including lung cancer. In this context, there is an urgent need to develop novel nanocarriers suitable for drug delivery by nebulization. To address this need, we synthesized and characterized a...

  • PLGA: A POLYMER OF CHOICE AS NANOCARRIER'S TO ACHIEVE EFFECTIVE DELIVERY OF MEDICINAL SUBSTANCES. Verma, Ajay; Ratnawat, Sanjay; Gupta, Arun K.; Jain, Sanjay // International Journal of Pharmaceutical Sciences & Research;Dec2012, Vol. 3 Issue 12, p5087 

    Poly (D,L-lactide-co-glycolic acid) the first synthetic biodegradable polymer used in surgery as resorbabe material, is also approved by USFDA for use in drug delivery. The nanoparticle composed of PLGA can be used for both controlled and targeted drug delivery. There are various grades of PLGA...

  • Efficient Chemotherapy of Rat Glioblastoma Using Doxorubicin-Loaded PLGA Nanoparticles with Different Stabilizers. Wohlfart, Stefanie; Khalansky, Alexander S.; Gelperina, Svetlana; Maksimenko, Olga; Bernreuther, Christian; Glatzel, Markus; Kreuter, Jörg // PLoS ONE;2011, Vol. 6 Issue 5, p1 

    Background: Chemotherapy of glioblastoma is largely ineffective as the blood-brain barrier (BBB) prevents entry of most anticancer agents into the brain. For an efficient treatment of glioblastomas it is necessary to deliver anti-cancer drugs across the intact BBB. Poly(lactic-co-glycolic acid)...

  • Fabrication of PLGA nanoparticles with a fluidic nanoprecipitation system. Hui Xie; Smith, Jeffrey W. // Journal of Nanobiotechnology;2010, Vol. 8, p18 

    Particle size is a key feature in determining performance of nanoparticles as drug carriers because it influences circulating half-life, cellular uptake and biodistribution. Because the size of particles has such a major impact on their performance, the uniformity of the particle population is...

  • Poly(D,L-lactide-co-glycolide) microcomposite containing magnetic iron core nanoparticles as a drug carrier. Naik, Sweta; Carpenter, Everett E. // Journal of Applied Physics;Apr2008, Vol. 103 Issue 7, p07A313 

    Today many potent anticancer drugs like cisplatin are available which carry a number of side effects. A promising way of reducing the side effects is to target the drug to tissue sites by coating it with biocompatible materials like Poly (dl-lactide-co-glycolide) (PLGA) polymer where controlled...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics