Preparation, characterization, and cytotoxicity of CPT/Fe2O3-embedded PLGA ultrafine composite fibers: a synergistic approach to develop promising anticancer material

Amna, Touseef; Hassan, M. Shamshi; Nam, Ki-Taek; Yang You Bing; Barakat, Nasser A. M.; Khil, Myung-Seob; Hak Yong Kim
January 2012
International Journal of Nanomedicine;2012, Vol. 7, p1659
Academic Journal
No abstract available.


Related Articles

  • Oral Delivery of DMAB-Modified Docetaxel-Loaded PLGA-TPGS Nanoparticles for Cancer Chemotherapy. Chen, Hongbo; Zheng, Yi; Tian, Ge; Tian, Yan; Zeng, Xiaowei; Liu, Gan; Liu, Kexin; Li, Lei; Li, Zhen; Mei, Lin; Huang, Laiqiang // Nanoscale Research Letters;Jan2011, Vol. 6 Issue 1, p1 

    Three types of nanoparticle formulation from biodegradable PLGA-TPGS random copolymer were developed in this research for oral administration of anticancer drugs, which include DMAB-modified PLGA nanoparticles, unmodified PLGA-TPGS nanoparticles and DMAB-modified PLGA-TPGS nanoparticles....

  • The Evaluation of the Possibilities of Using PLGA Co-Polymer and Its Composites with Carbon Fibers or Hydroxyapatite in the Bone Tissue Regeneration Process - in Vitro and in Vivo Examinations. Cieslik, Magdalena; Mertas, Anna; Morawska-Chochól, Anna; Sabat, Daniel; Orlicki, Rajmund; Owczarek, Aleksander; Król, Wojciech; Cieslik, Tadeusz // International Journal of Molecular Sciences;Jul2009, Vol. 10 Issue 7, p3224 

    Synthetic polymers belonging to the aliphatic polyester group have become highly promising biomaterials for reconstructive medicine. The purpose of the present work is a biological evaluation of lactide-glycolide co-polymer (PLGA) and its composites with carbon fibers (PLGA+CF) or hydroxyapatite...

  • In-vitro anticancer and antimicrobial activities of PLGA/silver nanofiber composites prepared by electrospinning. Almajhdi, Fahad; Fouad, H.; Khalil, Khalil; Awad, Hanem; Mohamed, Sahar; Elsarnagawy, T.; Albarrag, Ahmed; Al-Jassir, Fawzi; Abdo, Hany // Journal of Materials Science: Materials in Medicine;Apr2014, Vol. 25 Issue 4, p1045 

    In the present work, a series of 0, 1 and 7 wt% silver nano-particles (Ag NPs) incorporated poly lactic-co-glycolic acid (PLGA) nano-fibers were synthesized by the electrospinning process. The PLGA/Ag nano-fibers sheets were characterized using SEM, TEM and DSC analyses. The three synthesized...

  • Preparation and characterization of anticancer drug-loaded implantable PLGA microparticles. ÇETİN, Meltem; VURAL, İmran; ATİLA, Alptuğ; KADIOĞLU, Yücel // Turkish Journal of Chemistry;2010, Vol. 34 Issue 4, p509 

    This article describes the preparation and characterization of anticancer drug-loaded poly(lactide-coglycolide) (PLGA) microparticles. PLGA microparticles loaded with doxorubicin HCl (DOX) were prepared via o/w emulsion solvent evaporation. The release characteristics, encapsulation efficiency,...

  • Tailoring magnetic PLGA nanoparticles suitable for doxorubicin delivery. Tansık, Gülistan; Yakar, Arzu; Gündüz, Ufuk // Journal of Nanoparticle Research;Jan2014, Vol. 16 Issue 1, p1 

    One of the main problems of current cancer chemotherapy is the lack of selectivity of anti-cancer drugs to tumor cells, which leads to systemic toxicity and adverse side effects. In order to overcome these limitations, researches on controlled drug delivery systems have gained much attention....

  • High-Temperature Heat-Insulating Materials Based on Fibers from Basalt-Type Rock Materials. Novitskii, A. G. // Refractories & Industrial Ceramics;Mar/Apr2004, Vol. 45 Issue 2, p144 

    Comparative characteristics of fine and ultrafine fibers based on basalt-type rock materials are given and their resistance to high temperatures discussed. Optimum parameters for heat insulators prepared from a mix of different fibers are given. The importance of developing a technology for...

  • Development of Folate-Conjugated PEGylated Poly (d,l-lactide-co-glycolide) Nanoparticulate Carrier for Docetaxel. Murugesan, Senthilkumar; Mishra, Pradeep; Jain, Narendra Kumar // Current Nanoscience;Nov2008, Vol. 4 Issue 4, p402 

    In the present study we developed folate conjugated-PEGylated PLGA nanoparticles as an alternate carrier for Docetaxel (DTX) (antineoplastic agent). In order to investigate a more efficient delivery mode, the folate moiety was conjugated to PEGylated PLGA in two ways; firstly it was conjugated...

  • PLGA/nHA hybrid nanofiber scaffold as a nanocargo carrier of insulin for accelerating bone tissue regeneration. Haider, Adnan; Gupta, Kailash; Kang, Inn-Kyu // Nanoscale Research Letters;Dec2014, Vol. 9 Issue 1, p1 

    The development of tissue engineering in the field of orthopedic surgery is booming. Two fields of research in particular have emerged: approaches for tailoring the surface properties of implantable materials with osteoinductive factors as well as evaluation of the response of osteogenic cells...

  • Isolation of Spermatogonial Stem Cells from Tumoral cells by drug delivery. Shabani R.; Abolhasani F.; Ashtari K.; Ashjari M.; Izadyar F.; Behnam B.; Asadi E.; Koruji M. // Iranian Journal of Reproductive Medicine;Apr2015 Supplement, p28 

    Introduction: Testicular cancer is the most common cancer affecting men of reproductive age. Cisplatin is one of the majority helpful chemotherapeutic agents for treatment of this cancer. In addition, spermatogonial stem cells (SSCs) are necessary for the improvement of spermatogenesis...

  • Nanoparticles of Poly(Lactide-Co-Glycolide)-d-a-Tocopheryl Polyethylene Glycol 1000 Succinate Random Copolymer for Cancer Treatment. Yuandong Ma; Yi Zheng; Kexin Liu; Ge Tian; Yan Tian; Lei Xu; Fei Yan; Laiqiang Huang; Lin Mei // Nanoscale Research Letters;Jul2010, Vol. 5 Issue 7, p1161 

    Cancer is the leading cause of death worldwide. Nanomaterials and nanotechnologies could provide potential solutions. In this research, a novel biodegradable poly(lactide-co-glycolide)-d-a-tocopheryl polyethylene glycol 1000 succinate (PLGA-TPGS) random copolymer was synthesized from lactide,...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics