TITLE

Selective targeting of melanoma by PEG-masked protein-based multifunctional nanoparticles

AUTHOR(S)
Vannucci, Luca; Falvo, Elisabetta; Fornara, Manuela; Di Micco, Patrizio; Benada, Oldrich; Krizan, Jiri; Svoboda, Jan; Hulikova-Capkova, Katarina; Morea, Veronica; Boffi, Alberto; Ceci, Pierpaolo
PUB. DATE
January 2012
SOURCE
International Journal of Nanomedicine;2012, Vol. 7, p1489
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
No abstract available.
ACCESSION #
82508903

 

Related Articles

  • NANOTRANSPORTERS FOR ANTICANCER DRUG DELIVERY. Kopel, Pavel; Wawrzak, Dorota; Milosavljevic, Vedran; Moulick, Amitava; Vaculovicova, Marketa; Kizek, Rene; Adam, Vojtech // Nanotechnology Research Journal;2015, Vol. 8 Issue 1, p1 

    Nanomedicine is a relatively new field of medicine aiming to overcome usual problems that appear in disease treatment. Natural or artificial nanodevices, with dimensions similar to those of biological molecules in human body, can carry drugs more efficiently and mostly with no side effects on...

  • Conjugation of Magnetite Nanoparticles with Melanogenesis Substrate, NPrCAP Provides Melanoma Targeted, in Situ Peptide Vaccine Immunotherapy through HSP Production by Chemo-Thermotherapy. Jimbow, Kowichi; Tamura, Yasuaki; Yoneta, Akihiro; Kamiya, Takafumi; Ono, Ichiro; Yamashita, Toshiharu; Ito, Akira; Honda, Hiroyuki; Wakamatsu, Kazumasa; Ito, Shosuke; Nohara, Satoshi; Nakayama, Eiichi; Kobayashi, Takeshi // Journal of Biomaterials & Nanobiotechnology;Apr2012, Vol. 3 Issue 2, p140 

    In order to develop melanoma-targeted in situ peptide vaccine immunotherapy, magnetite nanoparticles were conjugated with a melanogenesis substrate, N-propionyl cysteaminylphenol (NPrCAP). Magnetite nanoparticles introduced thermotherapy which caused non-apoptotic cell death and generation of...

  • Multifunctional FePt Nanoparticles for Radiation-Guided Targeting and Imaging of Cancer. Hariri, Ghazal; Wellons, Matthew; Morris, William; Lukehart, Charles; Hallahan, Dennis // Annals of Biomedical Engineering;Mar2011, Vol. 39 Issue 3, p946 

    multifunctional FePt nanoparticle was developed that targets tumor microvasculature via 'radiation-guided' peptides, and is detected by both near-infrared (NIR) fluorescence imaging and analytical mass spectrometry methods. Tumor specific binding was first measured by biotinylated peptide linked...

  • Melanoma-Targeted Chemothermotherapy and In Situ Peptide Immunotherapy through HSP Production by Using Melanogenesis Substrate, NPrCAP, and Magnetite Nanoparticles. Kowichi Jimbow; Yasue Ishii-Osai; Shosuke Ito; Yasuaki Tamura; Akira Ito; Akihiro Yoneta; Takafumi Kamiya; Toshiharu Yamashita; Hiroyuki Honda; Kazumasa Wakamatsu; Katsutoshi Murase; Satoshi Nohara; Eiichi Nakayama; Takeo Hasegawa; Itsuo Yamamoto; Takeshi Kobayashi // Journal of Skin Cancer;2013, p1 

    Exploitation of biological properties unique to cancer cells may provide a novel approach to overcome difficult challenges to the treatment of advanced melanoma. In order to develop melanoma-targeted chemothermoimmunotherapy, a melanogenesis substrate, N-propionyl-4-S-cysteaminylphenol (NPrCAP),...

  • Fabrication of Heparinized Mesoporous Silica Nanoparticles as Multifunctional Drug Carriers. Yongxiang Zhang; Xinmin Liu; Yizhong Lu; Jincai Wang; Tingfang Dong; Xiaohong Liu // Journal of Chemistry;2013, p1 

    In this study, heparinized multifunctional mesoporous silica nanoparticles were successfully synthesized and characterized. The new material not only maintains intrinsic functions of bare magnetic and fluorescent mesoporous silica materials such as targeting, imaging, and sustained release of...

  • Modular Protein Engineering in Emerging Cancer Therapies. Vázquez, Esther; Ferrer-Miralles, Neus; Mangues, Ramón; Corchero, José Luis; Schwartz Jr., Simó; Villaverde, Antonio // Current Pharmaceutical Design;3/11/2009, Vol. 15 Issue 8, p893 

    An urgent need of more effective and personalized treatments for cancer and other genetic diseases is becoming a generalized claim. This is pushing forward experimental alternative approaches based on targeted nanoconjugates, which are designed to be specifically directed against target cells....

  • Advances in multifunctional magnetic nanoparticles. Sharma, Prashant K.; Dutta, Ranu K.; Pandey, Avinash C. // Advanced Materials Letters;Oct2011, Vol. 2 Issue 4, p246 

    Multifunctional magnetic nanoparticles have emerged as one of the important futuristic material for variety of applications starting from data storage, security/sensors to biomedical applications. The application of multifunctional magnetic nanoparticles in biological organisms has fashioned...

  • Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy. Srinivasan, Mathangi; Rajabi, Mehdi; Mousa, Shaker A. // Nanomaterials (2079-4991);2015, Vol. 5 Issue 4, p1690 

    The field of nanotechnology has led to the development of many innovative strategies for effective detection and treatment of cancer, overcoming limitations associated with conventional cancer diagnosis and therapy. Multifunctional nanoparticle systems can integrate imaging, targeting and...

  • Team finds stable RNA nano-scaffold within virus core.  // Biomedical Market Newsletter;9/26/2011, Vol. 21, p673 

    The article reports on the discovery of RNA nano-scaffolds by researchers from the University of Cincinnati (UC) in the U.S. which will serve as a platform for building larger, multifunctional nanoparticles to deliver therapeutics to targeted cells.

  • N-Propionyl-Cysteaminylphenol-Magnetite Conjugate (NPrCAP/M) Is a Nanoparticle for the Targeted Growth Suppression of Melanoma Cells. Sato, Makito; Yamashita, Toshiharu; Ohkura, Masae; Osai, Yasue; Sato, Akiko; Takada, Tomoaki; Matsusaka, Hidenobu; Ono, Ichiro; Tamura, Yasuaki; Sato, Noriyuki; Sasaki, Yasushi; Ito, Akira; Honda, Hiroyuki; Wakamatsu, Kazumasa; Ito, Shosuke; Jimbow, Kowichi // Journal of Investigative Dermatology;Sep2009, Vol. 129 Issue 9, p2233 

    A magnetite nanoparticle, NPrCAP/M, was produced for intracellular hyperthermia treatment of melanoma by conjugating N-propionyl-cysteaminylphenol (NPrCAP) with magnetite and used for the study of selective targeting and degradation of melanoma cells. NPrCAP/M, like NPrCAP, was integrated as a...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics