A self-assembling peptide RADA16-I integrated with spider fibroin uncrystalline motifs

Sun, Lijuan; Zhao, Xiaojun
January 2012
International Journal of Nanomedicine;2012, Vol. 7, p571
Academic Journal
No abstract available.


Related Articles

  • Self-Assembly from Low Dimension to Higher Conformation of GGX Motif in Spider Silk Protein. Qinghan Zhou; Juan Lin; Feng Yuan; Zhaoyang Ye; Feng Qiu; Chengkang Tang; Yongzhu Chen; Xiaojun Zhao // Current Nanoscience;Nov2009, Vol. 5 Issue 4, p457 

    Spider silk is intriguing because of its unique structure and high-performance mechanical properties. However, few studies have presented data characterizing the conserved motifs found in the silk protein as an oligopeptide. In this report a designed peptide that mimics the repetitive GGX motif...

  • Identification and synthesis of novel biomaterials based on spider structural silk fibers. Hsia, Yang; Gnesa, Eric; Tang, Simon; Jeffery, Felicia; Geurts, Paul; Zhao, Liang; Franz, Andreas; Vierra, Craig // Applied Physics A: Materials Science & Processing;Nov2011, Vol. 105 Issue 2, p301 

    The diversity in function and mechanical behavior of spider silks, and the ability to produce these silks recombinantly, have tremendous potential in creating a new class of biomimetic materials. Here we investigate the structural and mechanical properties of pyriform silks from the golden...

  • Got Silk? Summers, Adam // Natural History;Jul2001, Vol. 110 Issue 6, p64 

    Presents information on spider silk. Resiliency of spider silk; Comparison between the properties of dragline and capture spider silk; Potential industrial uses of fibroins, the proteins found in silk; Components of fibroin molecules.

  • Design, Expression and Solid-State NMR Characterization of Silk-Like Materials Constructed from Sequences of Spider Silk, Samia cynthia ricini and Bombyx mori Silk Fibroins. Mingying Yang; Asakura, Tetsuo // Journal of Biochemistry;Jun2005, Vol. 137 Issue 6, p721 

    Silk has a long history of use in medicine as sutures. To address the requirements of a mechanically robust and biocompatible material, basic research to clarify the role of repeated sequences in silk fibroin in its structures and properties seems important as well as the development of a...

  • Solution Structures of Two Homologous Venom Peptides from Sicarius dolichocephalus. Loening, Nikolaus M.; Wilson, Zachary N.; Zobel-Thropp, Pamela A.; Binford, Greta J. // PLoS ONE;Jan2013, Vol. 8 Issue 1, Special section p1 

    We present solution-state NMR structures for two putative venom peptides from Sicarius dolichocephalus. These peptides were identified from cDNA libraries created from venom gland mRNA and then recombinantly expressed. They are the first structures from any species of Sicarius spiders, and the...

  • Responsive gels formed by the spontaneous self-assemby of peptides into polymeric beta-sheet tapes. Aggeli, A.; Bell, M. // Nature;3/20/1997, Vol. 386 Issue 6622, p259 

    Demonstrates that a biological motif, the peptide beta-sheet, can be exploited in designed oligopeptides that self-assemble into polymeric tapes. Their potentially useful mechanical properties; Description of the construction of oligopeptides; The suggestion of the possibility of engineering a...

  • Characterization of unique heavy chain fibroin filaments spun underwater by the caddisfly Stenopsyche marmorata (Trichoptera; Stenopsychidae). Wang, Yujun; Sanai, Kazumi; Wen, Hongxiu; Zhao, Tianfu; Nakagaki, Masao // Molecular Biology Reports;Jul2010, Vol. 37 Issue 6, p2885 

    The silks of both Lepidoptera and its sister order Trichoptera contain a homologue of heavy chain (H-fibroin), which is assumed to determine the physical properties of the fiber, such as elasticity and toughness. The long repetitive region of the H-fibroin caddisfly Stenopsyche marmorata shows a...

  • A review on spider toxins a useful source of pharmacological peptides. Upadhyay, Ravi Kant; Ahmad, Shoeb // Journal of Pharmacy Research;Apr2011, Vol. 4 Issue 4, p1169 

    Spider venoms are complex mixtures or cocktails of toxic proteins and peptides that have been evolved during very long evolution. It is used by spiders for prey capture and/or defense. Spider venom shows variable pharmacological activity and affect various cell targets due to presence of diverse...

  • Spiders' fibers.  // International Wildlife;Sep/Oct85, Vol. 15 Issue 5, p51 

    Spider silk is composed of a type of protein called fibroin, which is indigestible to nearly any animal except spiders. Spider silk is more elastic than nylon, stronger than steel and impervious to mold or rot. Article discusses uses of the silk by both man and spider.

  • Surface Modification and Characterisation of Silk Fibroin Fabric Produced by the Layer-by-Layer Self-Assembly of Multilayer Alginate/Regenerated Silk Fibroin. Shen, Gaotian; Hu, Xingyou; Guan, Guoping; Wang, Lu // PLoS ONE;Apr2015, Vol. 10 Issue 4, p1 

    Silk-based medical products have a long history of use as a material for surgical sutures because of their desirable mechanical properties. However, silk fibroin fabric has been reported to be haemolytic when in direct contact with blood. The layer-by-layer self-assembly technique provides a...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics