Cardiovascular Risk Factors in Children from the Belgian Province of Luxembourg: The Belgian Luxembourg Child Study

Guillaume, Michèle; Lapidus, Leif; Beckers, François; Lambert, André; Bjömtorp, Per
January 1996
American Journal of Epidemiology;1996, Vol. 144 Issue 9, p867
Academic Journal
The Province of Luxembourg is an area in Belgium with a high prevalence of risk factors for cardiovascular disease and non-insulin-dependent diabetes mellitus among adults. In the present study, children in the age groups 6–8, 8–10, and 10–12 years were selected at random from school classes (n = 1, 028), with a participation rate of 70.3%. Anthropometric factors, blood pressure, and fasting blood glucose, plasma cholesterol, triglyceride, and insulin levels were measured in 1992. All anthropometric and metabolic variables increased with age, except for waist: hip circumference ratio in boys and cholesterol in girls. In the oldest group, girts who had passed menarche were taller and heavier and had greater skinfold, body mass index, insulin, and systolic blood pressure values but lower total cholesterol levels and waist: hip ratios than girls who had not passed menarche. Boys had lower skinfolds and higher waist: hip ratios than girls in all age groups, and were significantly shorter and lighter in the oldest age group. There was no difference in body mass index between the two sexes. Girls had higher triglyceride and insulin levels in the 10- to 12-year age group, lower blood glucose values in the 8–10 and 10–12 age groups, and lower diastolic blood pressures in the 8–10 age group. Obesity, blood glucose, triglycerides, insulin, and blood pressure were highly interrelated. Cholesterol, triglycerides, insulin, and blood pressure values were all among the highest of values previously reported in other studies. The deciles of body mass index above 50 appeared to be particularly elevated, suggesting that obesity, when present, was pronounced in this population of children. These findings suggest an accumulation of genetic susceptibility to cardiovascular disease and non-insulin-dependent diabetes mellitus in this stable, ethnically homogeneous, and rather isolated part of continental Europe. Am J Epidemiol 1996; 144: 867-80.


Related Articles

  • The Consequences of Lowering the Threshold for Impaired Fasting Glucose. Timar, Romulus; Serban, Viorel; Diaconu, Laura; Botea, Veronica; Vlad, Adrian; Timar, Bogdan // Diabetes;Jun2007 Supplement 1, Vol. 56, pA274 

    Background and Aims: IFG is an abnormal metabolic state associated with an elevated risk of developing DM. The evidences from large studies showed that IFG defined as FPG 110-125mg/dL failed to identify a number of individuals with IGT and increased risk for DM and cardiovascular disease. As a...

  • Cardiovascular risk factors in a Mexican middle-class urban population. The Lindavista Study. Baseline data. Meaney, Alejandra; Ceballos-Reyes, Guillermo; Gutierrez-Salmean, Gabriela; Samaniego-Méndez, Virginia; Vela-Huerta, Agustín; Alcocer, Luis; Zárate-Chavarría, Elisa; Mendoza-Castelán, Emma; Olivares-Corichi, Ivonne; García-Sánchez, Rubén; Martínez-Marroquín, Yolanda; Meaney, Eduardo // Archivos de Cardiología de México;oct-dic2013, Vol. 83 Issue 4, p249 

    Introduction and objective: The aim of this communication is to describe the cardiovascular risk factors affecting a Mexican urban middle-class population. Methods: A convenience sample of 2602 middle class urban subjects composed the cohort of the Lindavista Study, a prospective study aimed to...

  • Feasibility and Effectiveness in Clinical Practice of a Multifactorial Intervention for the Reduction of Cardiovascular Risk in Patients With Type 2 Diabetes. VACCARO, OLGA; FRANZINI, LAURA; MICCOLI, ROBERTO; CAVALOT, FRANCO; ARDIGÒ, DIEGO; BOEMI, MASSIMO; DE FEO, PIERPAOLO; REBOLDI, GIANPAOLO; RIVELLESE, ANGELA ALBAROSA; TROVATI, MARIELLA; ZAVARONI, IVANA // Diabetes Care;Sep2013, Vol. 36 Issue 9, p2566 

    OBJECTIVE--To evaluate the feasibility and effectiveness of an intensive, multifactorial cardiovascular risk reduction intervention in a clinic-based setting. RESEARCH DESIGN AND METHODS--The study was a pragmatic, cluster randomized trial, with the diabetes clinic as the unit of randomization....

  • Cardiovascular Risk Factors Among Youth With and Without Type 2 Diabetes. West, Nancy A.; Hamman, Richard F.; Mayer-Davis, Elizabeth J.; D'Agostino Jr., Ralph B.; Marcovina, Santica M.; Liese, Angela D.; Zeitler, Philip S.; Daniels, Stephen R.; Dabelea, Dana // Diabetes Care;Jan2009, Vol. 32 Issue 1, p175 

    OBJECTIVE -- To compare cardiovascular disease (CVD) risk factors among recently diagnosed youth with type 2 diabetes and nondiabetic youth and investigate whether demographic, behavioral, or metabolic factors might account for observed differences. RESEARCH DESIGN AND METHODS-- Data from 106...

  • Valoración del impacto de las actividades realizadas en la clínica de atención integral a pacientes hipertensos y diabéticos del Hospital Universitario de San Ignacio. DUARTE, ANDRÉS; BECERRA, NELCI ASTRID // Universitas Médica;abr-jun2009, Vol. 50 Issue 2, p156 

    Introduction: Chronic diseases, such as hypertension and diabetes, are by far one of the greatest public health problems in the world, and together with other cardiovascular risk factors as obesity, tobacco consumption, hyperlipidemia, among others, are the most important millennium epidemic....

  • Brachial-Ankle Pulse Wave Velocity as a Novel Measure of Arterial Stiffness: Present Evidences and Perspectives. Munakata, Masanori; Nunokawa, Tohru; Tayama, Jun; Yoshinaga, Kaoru; Toyota, Takayoshi // Current Hypertension Reviews;2005, Vol. 1 Issue 3, p223 

    Atherosclerotic cardiovascular disease is a leading cause of death in most developed countries. Cardiovascular risk factors such as hypertension, diabetes, and dyslipidemia initiate structural and functional abnormalities in the arterial wall, leading to the development of atherosclerosis....

  • INVEST: Systolic BP control not associated with improved CV outcomes in patients with CAD, diabetes.  // Cardiology Today;Sep2010, Vol. 13 Issue 9, p29 

    The article focuses on the International Verapamil SR-Trandolapril Study (INVEST) which found that there is no link between tight control of systolic blood pressure (BP) in individuals suffering from diabetes and coronary artery disease (CAD), and improved cardiovascular (CV) outcomes.

  • THE DIABETES ABC'S. Peterson, Kevin // Diabetes Forecast;Feb2003, Vol. 56 Issue 2, p49 

    Focuses on the relationship between diabetes and blood pressure and the management of high blood pressure. Chances of development of hypertension in diabetics as compared to nondiabetics; Risk of heart attacks and other problems due to hypertension; Steps to be taken to bring down blood...

  • Hypertension and Dyslipidemia in Type 2 Diabetes Mellitus in United Arab Emirates. Mathew, Elsheba; Ahmed, Maha; Hamid, Sumaira; Abdulla, Fatima; Batool, Khadija // Australasian Medical Journal;Nov2010, Vol. 3 Issue 11, p699 

    Background In United Arab Emirates (UAE), the prevalence of Diabetes Mellitus was 19.6% in 1998-2000. Co-morbidity with Hypertension (HT) and Dyslipidemia (DL) increases the probability of cardiovascular complications, and hence the study of the distribution of HT and DL in patients with type 2...

  • Triglyceride, albuminuria and blood pressure are the major associations of non-fatal cardiovascular disease in Chinese type 2 diabetes. Ko, G.T.C.; Chan, J.C.N.; Chow, C.C.; Yeung, V.T.F.; Chan, W.B.; So, W.Y.; Ma, R.C.W.; Ozaki, R.; Cockram, C.S. // Acta Diabetologica;Jun2003, Vol. 40 Issue 2, p80 

    Diabetes is associated with an increased risk of cardiovascular disease (CVD). We studied risk factors for CVD in a cohort of Chinese type 2 diabetic patients recruited between July 1994 and August 1998. Ischemic heart disease (IHD) was defined as a history of: (i) confirmed coronary artery...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics