TITLE

Real Time Observation of the Binding of Herpes Simplex Virus Type 1 (HSV-1) to Immobilized Heparan Sulfate and the Neutralization of HSV-1 by Sulfonated Human Immunoglobulin

AUTHOR(S)
Inoue, Kazuko; Arai, Toshihiko; Aoyagi, Masaaki
PUB. DATE
January 1996
SOURCE
Journal of Biochemistry;1996, Vol. 120 Issue 2, p233
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
A real time biomolecular interaction assay system involving an optical sensor was applied to quantitative analysis of the binding of herpes simplex virus type 1 (HSV-1) to immobilized heparan sulfate, a cellular receptor component of HSV-1, and the neutralization antibody titer against this virus with a commercially available sulfonated human immunoglobulin preparation. The virus titer in a viral solution and the neutralizing antibody titer in the human immunoglobulin preparation could be successfully estimated in a short time with this system without any difficult cell culture.
ACCESSION #
80117333

 

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