TITLE

Occupational exposure to dust: inflammation and ischaemic heart disease

AUTHOR(S)
Sjogren, Bengt
PUB. DATE
July 1997
SOURCE
Occupational & Environmental Medicine;Jul1997, Vol. 54 Issue 7, p466
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Objectives: To review the possible association between occupational exposure to dust and ischaemic heart disease (IHD). Methods: A literature search was per formed of relevant studies regarding IHD in specific exposures to dust. The chosen exposures were arsenic, asbestos, beryllium, lead, polycyclic aromatic hydrocarbons, and quartz. The chosen occupations were farmers, paper and paper pulp workers, sawyers, and welders. Discussion: A theory was launched in 1995 that urban particulate air pollution may provoke alveolar inflammation, with release of mediators capable of increasing blood coagulability in susceptible people and cause cardiovascular deaths. The present review expandsthis hypothesis and links occupational exposure to inhaled particleswith the occurrence of ischaemic heart disease. Conclusion: This hypothesis should be tested by comparing the concentrations of fibrinogen in workers exposed and non-exposed to particles with control for other possible confounders such as smoking habits.
ACCESSION #
8002951

 

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