In vitro Antimicrobial Activity Assessment of Zymox; Topical Cream Against Methicillin-Resistant Staphylococcus aureus (MRSA)

Atwal, Rajvinder; John, Smitha; Turcios, Stephanie
March 2010
International Journal of Applied Research in Veterinary Medicine;Mar2010, Vol. 8 Issue 1, p51
Academic Journal
The goal of this study was to determine the antibacterial effectiveness of Zymox� Topical Cream against Methicillin-Resistant Staphylococcus aureus (MRSA). The product was tested at 100% concentration using a log reduction method. Twenty mL of Zymox� Topical Cream (Product) and 20 mL of Phosphate buffer solution (Control) were added into separate centrifuge tubes and inoculated with the bacterial strain. At time intervals of 30 seconds, 1 minute, and 5 minutes the Product and Control were placed into a dilution of neutralizing broth. One milliliter from each of the dilutions was plated and incubated at 32.5 � 2.5�C to determine the number of microorganisms remaining at each time point. The test material, Zymox� Topical Cream, elicited a 100% reduction at 5 minutes. This represents a >3.0 log reductions at 5 minutes. The results of the study demonstrate Zymox� Topical Cream has antibacterial activity against MRSA at 5 minutes.


Related Articles

  • Synthesis and Biological Evaluation of New Pleuromutilin Derivatives as Antibacterial Agents. Ruo-Feng Shang; Guan-Hua Wang; Xi-Ming Xu; Si-Jie Liu; Chao Zhang; Yun-Peng Yi; Jian-Ping Liang; Yu Liu // Molecules;Nov2014, Vol. 19 Issue 11, p19050 

    Several pleuromutilin derivatives possessing thiadiazole moieties were synthesized via acylation reactions under mild conditions. The in vitro antibacterial activities of the derivatives against methicillin-resistant S. aureus, methicillin-resistant S. epidermidis, S. aureus, S. epidermidis, E....

  • Efficacy of continuous infusion of vancomycin for the outpatient treatment of methicillin-resistant Staphylococcus aureus infections. Verrall, Ayesha J.; Llorin, Ryan; Tam, Vincent H.; Lye, David C.; Sulaiman, Zuraidah; Zhong, Lihua; Archuleta, Sophia; Fisher, Dale A. // Journal of Antimicrobial Chemotherapy (JAC);Dec2012, Vol. 67 Issue 12, p2970 

    Objectives Recently published guidelines on the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections recommend against administering vancomycin by continuous infusion on the basis of insufficient studies comparing this with intermittent infusion. We compared outcomes of...

  • Persistence Pays off Developing Antibiotic Against Persisters. Breindl, Anette // BioWorld Today;11/15/2013, Vol. 24 Issue 221, p1 

    The article reports on a study published in the November 14, 2013 issue of the science journal "Nature" which found that a combination of antimicrobial drugs acyldepsipeptide-4 (ADEP-4) and rifampicin can eradicate Staphylococcus aureus biofilms. It informs that the combination therapy is...

  • Daptomycin resistance in methicillin-resistant Staphylococcus aureus: a report from Southern India. Vamsimohan, Anantabotla; Gupta, Soham; Muralidharan, Sethumadhavan // Germs;Sep2014, Vol. 4 Issue 3, p70 

    The article discusses the results of a research study on the resistance of methicillin-resistant Staphylococcus aureus (MRSA) in daptomycin in patients in southern India. Topics mentioned include the aerobic culture and sensitivity profiling of isolates of Staphylococcus aureus, antibiotic...

  • Alternative treatment of methicillin-resistant Staphylococcus aureus and extended spectrum beta-lactamases producing multiresistant gram-negative bacteria from nosocomial infection by Marrubium vulgare methanolic compounds. Temmouri, H. Benfreha; Meddah, A. Tirtouil; Sahraoui, T.; Meddah, B. // Journal of Chemical & Pharmaceutical Research;2014, Vol. 6 Issue 6, p60 

    The emergence of the multiresistant bacteria responsible of nosocomial infections (NI) represented a real public health problem. These germs are the pathogenic opportunist ones such as the Methicillin-Resistant Staphylococcus aureus (MRSA) and Extended Spectrum Beta-Lactamases producing...

  • Pathogens in Eye Care. Bartlett, Jimmy D. // Review of Optometry;Nov2013, Vol. 150 Issue 11, p24 

    The article discusses methicillin-resistant Staphylococcus aureus (MRSA), a potentially lethal bacteria resistant to some conventional antibiotics, with special focus given to ophthalmic infections caused by it. Challenges for the prevention, diagnosis and treatment of MRSA-caused eye conditions...

  • Prevalence of and Risk Factors for Methicillin-Resistant Staphylococcus aureus Colonization in HIV Infection: A Meta-Analysis. Zervou, Fainareti N.; Zacharioudakis, Ioannis M.; Ziakas, Panayiotis D.; Rich, Josiah D.; Mylonakis, Eleftherios // Clinical Infectious Diseases;Nov2014, Vol. 59 Issue 9, p1302 

    Among individuals with HIV, 6.9% are colonized with methicillin-resistant Staphylococcus aureus (MRSA). Exposure to healthcare settings and correctional facilities significantly increases MRSA colonization risk. Screening of extranasal sites increases the number of identified MRSA carriers by at...

  • Methicillin-Resistant Staphylococcus aureus Guidelines: A Myriad of Open Questions. Cadena, Jose; Restrepo, Marcos I. // Clinical Infectious Diseases;7/1/2011, Vol. 53 Issue 1, p97 

    A letter to the editor is presented in response to an article on the guidelines released by the Infectious Diseases Society of America (IDSA) for the treatment of methicillin-resistant Staphylococcus aureus (MRSA), in a previous issue of the periodical.

  • Rifampin and Methicillin-Resistant Staphylococcus aureus Bone and Joint Infections. Johnson, James R. // Clinical Infectious Diseases;7/1/2011, Vol. 53 Issue 1, p98 

    A letter to the editor related to the guidelines released by the Infectious Diseases Society of America (IDSA) for the treatment of rifampin and methicillin-resistant staphylococcus aureus (MRSA) bone and joint infections is presented.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics