Headache symptoms and indoor environmental parameters: Results from the EPA BASE study

Tietjen, Gretchen E.; Khubchandani, Jagdish; Ghosh, Somik; Bhattacharjee, Suchismita; Kleinfelder, Joann
August 2012
Annals of Indian Academy of Neurology;Aug2012 Supplement, pS95
Academic Journal
Objective: The objective of this investigation was to determine the prevalence of migraine and headache symptoms in a national sample of US office employees. Also, we explored the association of headache symptoms with indoor environmental parameters of the work place. Background: Sick building syndrome (SBS), which includes headache, is a common global phenomenon, but the underlying environmental cause is uncertain. Materials and Methods: We used data from the 1994-1998 US Environmental Protection Agency's (EPA) Building Assessment and Survey Evaluation, a cross-sectional study of workers employed in 100 public and private office buildings across 25 states. The study used a self-administered questionnaire to assess headache frequency and prevalence of self-reported physician-diagnosed (SRPD) migraine. Indoor environmental parameters (IEP) were collected per EPA protocol from each building over a 1-week period and included carbon dioxide, carbon monoxide, temperature, relative humidity, particulate matter, volatile organic compound, illuminance, and sound level. The standards of American Society of Heating, Refrigerating and Air Conditioning Engineers were used to categorize IEP as either within- or out-of-comfort range for human dwelling. These limits delineate whether a parameter value is safe for human dwelling. Out-of-comfort range IEPs are associated with SBS and other human diseases. SRPD migraine and headache frequency were the primary outcome measures of the study. Multivariate logistic regression analyses were employed for the purpose of assessing the association between the outcome variable and IEPs. Results: Of the 4326 participants, 66% were females and 60% were between 30 and 49 years. Headache frequency during the last 4 weeks was as follows: None in 31%, 1-3 days in 38%, 1-3 days per week in 18%, and every or almost every workday in 8%. Females had higher SRPD migraine prevalence compared to males (27% vs. 11%, P<0.001) and were more likely to report any headache in the last month compared to males (75% vs. 53%, P<0.001). Odds of SRPD migraine were higher (P<0.05) for those exposed to IEP out-of-comfort range, and odds of exposure to out-of-comfort range IEPs were higher in groups who reported higher headache frequencies. Conclusions: Migraine diagnosis and elevated headache frequency are associated with an uncomfortable indoor environment. Periodic assessments and adjustments of IEP may have a beneficial impact on employees who are vulnerable to SBS.


Related Articles

  • Factors associated to the imposition of types of violence against women informed in sentry services. Jane Eyre de Souza Vieira, Luiza; Cameiro Ferreira, Renata; Alves Remigio Moreira, Gracyelle; Paula Soares Gondim, Ana; Alix Leite Araujo, Maria; Magalhães da Silva, Raimunda // Revista Latino-Americana de Enfermagem (RLAE);Jul/Aug2013, Vol. 21 Issue 4, p920 

    Objective: to identify the prevalence and the factors associated to the imposition of the different types of violence against women informed in sentry services. Method: transversal study accomplished through 939 notification forms of cases of violence against women, referring to the three years...

  • Home Renovation, Family History of Atopy, and Respiratory Symptoms and Asthma Among Children Living in China. Guang-Hui Dong; Zhengmin (Min) Qian; Jing Wang; Trevathan, Edwin; Miao-Miao Liu; Da Wang; Wan-Hui Ren; Weiqing Chen; Maayan Simckes; Alan Zelicoff // American Journal of Public Health;Oct2014, Vol. 104 Issue 10, p1920 

    Objectives. To investigate the association of indoor air pollution with the respiratory health of children, we evaluated the associations of children’s respiratory symptoms with asthma and recent home renovation. Methods. We conducted a cross-sectional survey in a school recruitment...

  • Evaluation of IL-8 gene polymorphisms in patients with periodontitis in Hamedan, Iran. Houshmand, Behzad; Hajilooi, Mehrdad; Rafiei, Alireza; Bidgoli, Mohsen; Soheilifar, Sara // Dental Research Journal;Jul2012, Vol. 9 Issue 4, p427 

    Background: Many environmental and genetic factors are known as factors that increase the susceptibility to periodontitis. As IL-8 is a chemokine that mediate the inflammatory process in periodontal disease, we decided to evaluate the effect of its polymorphism on chronic and aggressive...

  • Characteristics of Alcoholics Attending ‘Clubs of Alcoholics in Treatment’ in Italy: A National Survey. Curzio, Olivia; Tilli, Angela; Mezzasalma, Lorena; Scalese, Marco; Fortunato, Loredana; Potente, Roberta; Guidoni, Guido; Molinaro, Sabrina // Alcohol & Alcoholism;May/Jun2012, Vol. 47 Issue 3, p317 

    Aims: To provide an overview of alcoholics attending a socio-ecological treatment programme [Clubs of Alcoholics in Treatment (CATs)] and to identify factors associated with abstinence and self-perceived improvement in lifestyle. Methods: A national sample of 7522 subjects (76% males and 24%...

  • The pattern of physical comorbidity and the psychosocial determinants of depression: a prospective cohort study on a representative sample of family practice attendees in Slovenia. Selič, Polona; Švab, Igor; Rifel, Janez; Pavlič, Danica Rotar; King, Michael; Nazareth, Irwin; Černe, Anja // Mental Health in Family Medicine;2011, Vol. 8 Issue 3, p147 

    Objectives This study aims to present the patterns of physical comorbidity in depressed patients and factors strongly associated with depression in a representative sample of Slovenian family practice attendees. Methods Medical data was obtained for 911 general practice attendees. Of them, 221...

  • Disparate Patterns of Prenatal Care Utilization Stratified by Medical and Psychosocial Risk. Krans, Elizabeth; Davis, Matthew; Palladino, Christie // Maternal & Child Health Journal;May2013, Vol. 17 Issue 4, p639 

    To evaluate patterns of prenatal care utilization stratified by medical and psychosocial risk. A retrospective cohort of 786 pregnant women who subsequently delivered live births from 1999 to 2003 at the University of Michigan were classified into high medical, high psychosocial, high medical...

  • Educational status and patterns of weight gain in adulthood in Brazil: Estudo Pró-Saúde. de Jesus Mendes da Fonseca, Maria; de Figueiredo França, Rosana; Faerstein, Eduardo; Werneck, Guilherme Loureiro; Chor, Dóra // Pan American Journal of Public Health;Nov2012, Vol. 32 Issue 5, p376 

    The aim of the present study was to investigate the association between participant and parental educational status (considered as an indicator of socioeconomic status) and participant pattern of weight gain in adulthood. We analyzed data from 2 582 baseline participants (1999) of Estudo...

  • Does parkland influence walking? The relationship between area of parkland and walking trips in Melbourne, Australia. King, Tania L.; Thornton, Lukar E.; Bentley, Rebecca J.; Kavanagh, Anne M. // International Journal of Behavioral Nutrition & Physical Activit;2012, Vol. 9, p115 

    Background: Using two different measures of park area, at three buffer distances, we sought to investigate the ways in which park area and proximity to parks, are related to the frequency of walking (for all purposes) in Australian adults. Little previous research has been conducted in this...

  • Religious Participation and DSM IV Major Depressive Disorder Among Black Caribbeans in the United States. Taylor, Robert; Chatters, Linda; Nguyen, Ann // Journal of Immigrant & Minority Health;Oct2013, Vol. 15 Issue 5, p903 

    This study examines the relationship between religious involvement and 12-month and lifetime DSM-IV major depressive disorder (MDD) within a nationally representative sample of Black Caribbean adults. MDD was assessed using the DSM-IV World Mental Health Composite International Diagnostic...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics