TITLE

OnabotulinumtoxinA (BOTOX®): A Guide to Its Use in Preventing Headaches in Adults with Chronic Migraine

AUTHOR(S)
Lyseng-Williamson, Katherine A.; Frampton, James E.
PUB. DATE
August 2012
SOURCE
CNS Drugs;2012, Vol. 26 Issue 8, p717
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Intramuscular onabotulinumtoxinA (onaBoNTA; BOTOX®) is indicated for headache prophylaxis in adults with chronic migraine. According to pooled results from two large trials, treatment with up to five cycles of ona-BoNTA (155-195 units/cycle) at 12-week intervals was effective in reducing headache symptoms, decreasing headache-related disability and improving health-related quality of life in patients with chronic migraine. OnaBoNTA was generally well tolerated in these trials, with an adverse event profile that was consistent with that of the neurotoxin when injected into head and neck muscles
ACCESSION #
79451360

 

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