Volatile Organic Compounds in Exhaled Breath as Biomarkers for the Early Detection and Screening of Lung Cancer

Tisch, Ulrike; Billan, Salem; Ilouze, Maya; Phillips, Michael; Peled, Nir; Haick, Hossam
May 2012
Current Medical Literature: Lung Cancer;2012, Vol. 5 Issue 4, p107
Academic Journal
The article offers information on detection and screening of lung cancer. Staging of this disease can be classified according to the tumor, node and metastasis (TNM). It notes that most lung cancers originate from epithelial cells, and can be classified as small-cell lung carcinoma (SCLC), squamous cell carcinoma or large cell carcinoma. Lung cancer can be diagnosed through computed tomography (CT) and positron emission tomography (PET).


Related Articles

  • Skull destruction from intracranial metastasis arising from pulmonary squamous cell carcinoma: a case report. Kader, Imran; Strong, Michael; George, Mathew // Journal of Medical Case Reports;2013, Vol. 7 Issue 1, p1 

    Introduction: Squamous cell carcinoma of the lung represents 30% of all non-small cell lung carcinomas. It arises from dysplasia of squamous epithelium of the bronchi and is strongly associated with cigarette smoking. Squamous cell carcinoma of the lung is known to produce metastases in the...

  • FDG PET during radiochemotherapy is predictive of outcome at 1 year in non-small-cell lung cancer patients: a prospective multicentre study (RTEP2). Vera, Pierre; Mezzani-Saillard, Sandrine; Edet-Sanson, Agathe; Ménard, Jean-François; Modzelewski, Romain; Thureau, Sebastien; Meyer, Marc-Etienne; Jalali, Khadija; Bardet, Stéphane; Lerouge, Delphine; Houzard, Claire; Mornex, Françoise; Olivier, Pierre; Faure, Guillaume; Rousseau, Caroline; Mahé, Marc-André; Gomez, Philippe; Brenot-Rossi, Isabelle; Salem, Naji; Dubray, Bernard // European Journal of Nuclear Medicine & Molecular Imaging;Jun2014, Vol. 41 Issue 6, p1057 

    Purpose: To assess prospectively the prognostic value of FDG PET/CT during curative-intent radiotherapy (RT) with or without concomitant chemotherapy in patients with non-small-cell lung cancer (NSCLC). Methods: Patients with histological proof of invasive localized NSCLC and evaluable tumour,...

  • Rola pozytonowej tomografii emisyjnej (PET) w planowaniu radioterapii. Cytawa, Wojciech // Polish Oncology / Onkologia Polska;2012, Vol. 15 Issue 3, p103 

    The effectiveness of radiotherapy is highly dependent on precise target volume delineation. Apart from computed tomography which is a "gold standard" in radiotherapy planning,: other imaging modalities, such as positron emission tomography (PET), begin to play an important role in this process....

  • Hidden treasures in "ancient" microarrays: gene-expression portrays biology and potential resistance pathways of major lung cancer subtypes and normal tissue. Kerkentzes, Konstantinos; Tsamardinos, Ioannis; Lagani, Vincenzo; Vyberg, Mogens; Røe, Oluf Dimitri // Frontiers in Oncology;Sep2014, Vol. 4, p1 

    Objective: Novel statistical methods and increasingly more accurate gene annotations can transform "old" biological data into a renewed source of knowledge with potential clinical relevance. Here, we provide an in silico proof-of-concept by extracting novel information from a high-quality mRNA...

  • PET staging may reduce SCLC treatment costs.  // PharmacoEconomics & Outcomes News;5/26/2012, Issue 654, p6 

    The article discusses the effectiveness of positron emission tomography (PET) compared with conventional staging in the treatment of small-cell lung cancer, referencing a study by J. D. Ruben and colleagues published on the April 24, 2012 issue of the "Journal of Thoracic Oncology."

  • Reproducibility of quantitative 18F-3′-deoxy-3′-fluorothymidine measurements using positron emission tomography. de Langen, Adrianus J.; Klabbers, Bianca; Lubberink, Mark; Boellaard, Ronald; Spreeuwenberg, Marieke D.; Slotman, Ben J.; de Bree, Remco; Smit, Egbert F.; Hoekstra, Otto S.; Lammertsma, Adriaan A. // European Journal of Nuclear Medicine & Molecular Imaging;Mar2009, Vol. 36 Issue 3, p389 

    Positron emission tomography (PET) using 18F-3′-deoxy-3′-fluorothymidine ([18F]FLT) allows noninvasive monitoring of tumour proliferation. For serial imaging in individual patients, good reproducibility is essential. The purpose of the present study was to evaluate the...

  • Role of integrated F-18 fluoro-deoxy-glucose positron emission tomography and computed tomography in evaluation of lung cancer. Šobić-Šaranović, Dragana // Archive of Oncology;Dec2012, Vol. 20 Issue 3/4, p107 

    Lung cancer is one of the leading causes of death in the world. It is generally divided in two groups: non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Positron emission tomography (PET)/CT using the glucose analogue labeled with 18-fluor (F-18): fluoro-deoxy-glucose...

  • Mixed Anaplastic Small-Cell and Squamous-Cell Carcinoma of the Lung. Brereton, Harmar D.; Mathews, Mary M.; Costa, Jose; Kent, Harry; Johnson, Ralph E. // Annals of Internal Medicine;Jun78, Vol. 88 Issue 6, p805 

    Discusses the association of small-cell anaplastic and squamous-cell lung cancer in an autopsy series. Description of patients examined; Barries to the demonstration of squamous- and small-cell elements within the same tumor.

  • Stereotactic body radiation therapy for stage I non-small cell lung cancer: a small academic hospital experience. Witten, Matthew R.; Gittleman, Alicia E.; Catell, Donna T.; Haas, Jonathan A.; Factor, Oren B.; Vu, Charles C.; Schneider, Jeffrey G.; Schubach, Scott L. // Frontiers in Oncology;Oct2014, Vol. 4, p1 

    Purpose/Objective(s): Stereotactic body radiation therapy (SBRT) has been shown to have increased local control and overall survival relative to conventional external beam radiation therapy in patients with medically inoperable stage I non-small cell lung cancer (NSCLC). Excellent rates of local...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics