TITLE

Update on bacterial nosocomial infections

AUTHOR(S)
Bereket, W.; Hemalatha, K.; Getenet, B.; Wondwossen, T.; Solomon, A.; Zeynudin, A.; Kannan, S.
PUB. DATE
August 2012
SOURCE
European Review for Medical & Pharmacological Sciences;2012, Vol. 16 Issue 8, p1039
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
With increasing use of antimicrobial agents and advance in lifesaving medical practices which expose the patients for invasive procedures, are associated with the ever increasing of nosocomial infections. Despite an effort in hospital infection control measures, health care associated infections are associated with significant morbidity and mortality adding additional health care expenditure which may leads to an economic crisis. The problem is further complicated with the emergence of difficult to treat multidrug resistant (MDR) microorganism in the hospital environment. Virtually every pathogen has the potential to cause infection in hospitalized patients but only limited number of both gram positive and gram negative bacteria are responsible for the majority of nosocomial infection. Among them Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Enterococci takes the leading. Many intrinsic and extrinsic factors predispose hospitalized patients for these pathogens. Following simple hospital hygienic practices and strictly following standard medical procedures greatly reduces infection to a significant level although not all nosocomial infections are avoidable. The clinical spectrum caused by nosocomial pathogens depend on body site of infection, the involving pathogen and the patient's underlying condition. Structural and non structural virulence factors associated with the bacteria are responsible for the observed clinical manifestation. Bacteria isolation and characterization from appropriate clinical materials with antimicrobial susceptibility testing is the standard of laboratory diagnosis.
ACCESSION #
78327756

 

Related Articles

  • Prevalence of Pseudomonas aeruginosa in Post-operative Wound Infection in a Referral Hospital in Haryana, India. Prabhat Ranjan, K.; Ranjan, Neelima; Bansal, Satish K.; Arora, D R. // Journal of Laboratory Physicians;Jul-Dec2010, Vol. 2 Issue 2, p74 

    Background: The objective of our study was to determine the prevalence of Pseudomonas aeruginosa in the isolates of postoperative wound and its susceptibility pattern to commonly used antibiotics. Materials and Methods: During a 2-year period, specimens were received as postoperative wound swabs...

  • Synthesis, Characterization and evaluation of Antibacterial Activity of some 3-Substitutedphenylquinazoline -2,4-diones. Zaranappa; Vagdevi, H. M.; Jayanna, N. D.; Latha, K. P. // Der Pharma Chemica;2012, Vol. 4 Issue 4, p1754 

    In the present study a series of 3-substitutedphenylquinazoline-2,4-diones 1(a-m) have been synthesized from isatoic anhydride with substituted aromatic amines. The structure of these compounds has been established on the basis of their analytical and spectral data. All the compounds have been...

  • Antimicrobial susceptibility pattern of Staphylococcus aureus isolated from clinical specimens in Northern area of Jordan. Al-Zoubi, Mazhar Salim; Al-Tayyar, Ibrahim Ali; Hussein, Emad; Jabali, Alla Al; Khudairat, Salih // Iranian Journal of Microbiology;Oct2015, Vol. 7 Issue 5, p265 

    Background and Objectives: The global spread of methicillin resistant Staphylococcus aureus (MRSA) constitutes one of the most serious contemporary challenges to the treatment of hospital-acquired infections. We aimed to screen and assess the antibiotic susceptibility pattern of Staphylococcus...

  • Antibacterial and antioxidant investigations of Hallea ledermannii leaf extract. Adesegun, S. Adeleke; Anyika, N. Emmanuel; Adekoya, T. Oluseyi; Essien, S. Godwin // Indian Journal of Science & Technology;Jan2012, Vol. 5 Issue 1, p1885 

    Hallea ledermannii (Krause) Verdc. (Rubiaceae) is used for treatment of various microbial diseases such as dysentery and skin infections. The leaf extract was screened for antibacterial activities using agar cup plate method against pathogenic organisms like Staphylococcus aureus, Bacillus...

  • Antimicrobial Activity of Seaweeds Against Multi Drug Resistant Strains. Manikandan, S.; Ganesapandian, S.; Singh, Manoj; Sangeetha, N.; Kumaraguru, A. K. // International Journal of Pharmacology;2011, Vol. 7 Issue 4, p522 

    Nowadays, emergence of bacterial resistance poses a significant clinical problem. Hence, the aim of this study was to describe the current susceptibility patterns of Multi Drugs Resistant (MDR) strains of Urinary Tract Infections (UTI) isolates to current chemotherapeutic agents, as well as to...

  • Anti-biofilm and anti-adherence activity of Glm-U inhibitors. SUMAN, ETHEL; D'SOUZA, SUSHMA JANET; JACOB, PYARI; SUSHRUTH, M. R.; KOTIAN, M. SHASHIDHAR // Indian Journal of Medical Sciences;Sep2011, Vol. 65 Issue 9, p387 

    Background: Intravascular catheters and urinary catheters are an important source of hospital-acquired infections. Many microorganisms colonize indwelling catheters, including central venous catheters (CVCs) forming biofilms and cause infections that are difficult to treat. Although...

  • The transition from iron starvation to iron sufficiency as an important step in the progression of infection. Dauros-Singorenko, Priscila; Swift, Simon // Science Progress;Dec2014, Vol. 97 Issue 4, p371 

    Iron is an essential micronutrient for microbial life. At the start of an infection the host environment will normally restrict available iron, and innate immune responses will aim to further reduce iron, thus inhibiting growth of potential pathogens. Successful pathogens have developed a...

  • Wirksamkeit von Octenidin und Chlorhexidin in der artifiziell kontaminierten 3-D-Kultur mit humanen Keratinocyten. Müller, Gerald; Kramer, Axel; Siebert, Jörg // GMS Krankenhaushygiene Interdisziplinaer;2009, Vol. 4, p1 

    Epidermis-Equivalents (EpiDerm) derived from human keratinocytes were obtained after 14 d air-lift-culture. These In-vitro-models were used for the demonstration of a possible postantiseptic effect against the test microorganisms Pseudomonas aerudinosa and Staphylococcus aureus after 5 min...

  • In vitro Study of Honey Antimicrobial Activity. Moţ, Daniela // Scientific Papers: Animal Science & Biotechnologies / Lucrari St;2015, Vol. 48 Issue 1, p262 

    From ancient times honey was renowned for healing properties both in internal consumption and of external applications. Samples of non-standardized honey obtained direct from beekeeper were used in a study using a method of growth inhibition in the culture medium of microorganisms. In this aim...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics