TITLE

Aedes aegypti Saliva Enhances Dengue Virus Infection of Human Keratinocytes by Suppressing Innate Immune Responses

AUTHOR(S)
Surasombatpattana, Pornapat; Patramool, Sirilaksana; Luplertlop, Natthanej; Yssel, Hans; Missé, Dorothée
PUB. DATE
August 2012
SOURCE
Journal of Investigative Dermatology;Aug2012, Vol. 132 Issue 8, p2103
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses the role of dengue virus (DENV) vector mosquito Aedes aegypti's saliva in the enhancement of dengue virus infection in Human keratinocytes. DENV is a single-stranded RNA virus that belongs to the Flaviviridae family and causes dengue hemorrhagic fever and dengue shock syndrome. During blood feeding, an infected mosquito transmits virus in saliva in the uppermost layer of skin, the epidermis, which consists primarily of keratinocytes.
ACCESSION #
77727513

 

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