ATL>Gastric polyps in pediatrics: an 18-year hospital-based analysis

Attard, T.M.; Yardley, J.H.; Cuffari, C.
February 2002
American Journal of Gastroenterology;Feb2002, Vol. 97 Issue 2, p298
Academic Journal
OBJECTIVE:Gastric polyps are recognized as either an incidental finding on routine gastroscopy or a frequent occurrence in patients with polyposis syndromes. The aim of this study is to determine the prevalence, clinical presentation, and histological subclassification of gastric polyps identified on esophagogastroduodenoscopy in pediatric patients.METHODS:We performed an 18-yr retrospective study of all pediatric (<21 yr) patients with gastric polyps diagnosed between 1983 and 2000 at The Johns Hopkins Children’s Center. The histology slides were all evaluated at the time of the study according to the accepted histological classification of gastric polyps.RESULTS:Gastric polyps were reported in 40 procedures (0.07%) performed in 35 (male:female 1.3:1) patients with a mean (SEM) age at diagnosis of 14.4 (0.9) yr. Polyps were more frequent in white than in black patients (adjusted ratio 1.4:1). The histological subtypes included hyperplastic-inflammatory (42%), fundic gland (40%), hamartomatous (10%), adenomatous (5%), and heterotopic polyps (3%). Fundic gland polyps were frequently encountered in patients with familial adenomatous polyposis (81%). These patients tended to be asymptomatic at the time of their surveillance esophagogastroduodenoscopy, and frequently harbored histological changes of either dysplasia (31%) or indeterminate of dysplasia (19%).CONCLUSIONS:Hyperplastic polyps are the most frequently identified gastric polyps in our pediatric population. Fundic gland polyps are common in patients with familial adenomatous polyposis wherein they tend to harbor histological changes of dysplasia. Future longitudinal studies are needed to evaluate the temporal progression of dysplasia to gastric cancer in patients with fundic gland polyps, and to establish esophagogastroduodenoscopy surveillance guidelines.


Related Articles

  • Negative Biopsy after Referral for Biopsy-Proven Gastric Cancer. Chung Hyun Tae; Jun Haeng Lee; Byung-Hoon Min; Kyoung-Mee Kim; Poong-Lyul Rhee; Kim, Jae J. // Gut & Liver;Jan2016, Vol. 10 Issue 1, p63 

    Background/Aims: Repeat endoscopy with biopsy is often performed in patients with previously diagnosed gastric cancer to determine further treatment plans. However, biopsy results may differ from the original pathologic report. We reviewed patients who had a negative biopsy after referral for...

  • Gastric Diverticula: Congenital and Acquired. Eras, Philip; Beranbaum, Samuel L. // American Journal of Gastroenterology;Feb1972, Vol. 57 Issue 2, p120 

    Gastric diverticula of the juxtacardiac region which have a smooth configuration and no evidence of infiltration or inflammation should be regarded as congenital in origin and treated as benign structures. Designation of true or false serves no useful purpose. Pouches resembling gastric...

  • Impact of cumulative time on the clinical outcomes of endoscopic submucosal dissection in gastric neoplasm. Lim, Sun; Park, Jun; Lee, Hyuk; Shin, Sung; Lee, Sang; Lee, Yong // Surgical Endoscopy;Apr2013, Vol. 27 Issue 4, p1397 

    Background: Endoscopic submucosal dissection (ESD) can be technically demanding and requires great attention to detail and prolonged concentration. We assumed that clinical outcomes of ESDs may be affected by cumulative time, and we aimed to compare complete resection rates and adverse events...

  • The Morphological Effects of Chenodeoxycholic Acid on Human Gastric Mucosa. Sawyer, William R.; Ritter, Edward; Faloon, William W. // American Journal of Gastroenterology;May1984, Vol. 79 Issue 5, p348 

    Morphology of human gastric mucosa was examined by light microscopy before and after exposure to suspensions of chenodeoxycholic acid tablets. During gastroscopy with a flexible instrument the gastric mucosa of eight control subjects without gastric disease was biopsied. In five other patients...

  • Electrical stimulation for gastroparesis. de Csepel, J.; Goldfarb, B.; Shapsis, A.; Goff, S.; Gabriel, N.; Eng, H. M. // Surgical Endoscopy;Feb2006, Vol. 20 Issue 2, p302 

    Background: Gastroparesis is a disabling, and sometimes fatal, disease that often does not respond to medical treatment. This single-surgeon prospective study examines the safety and 6-month efficacy of electrical stimulation for the treatment of gastroparesis. Methods: Sixteen patients with...

  • A CRITICAL EVALUATION OF ROENTGENOLOGY AND GASTROSCOPY IN THE DIAGNOSIS OF GASTRIC DISORDERS. Rossien, A. Xerxes; Stanton, Arnold // American Journal of Gastroenterology;May1958, Vol. 29 Issue 5, p499 

    Compares the effectiveness of roentgenology and gastroscopy in diagnosing patients with gastric disorders. Strategy to reduce the limitations of gastroscopy; Examples of cases wherein gastroscopy should be utilized; Results of the comparative evaluation of gastric roentgenologic and gastropic...

  • gastric erosion. Peters, Michael // BMA A-Z Family Medical Encyclopedia;2004, p331 

    An encyclopedia entry for "gastric erosion" is presented. It refers to a break in the surface layer of the membrane that lines the stomach. The condition occurs in some cases of gastritis. Many result from intake of irritants such as alcohol, iron tablets, or aspirin. Often there are no...

  • gastritis. Peters, Michael // BMA A-Z Family Medical Encyclopedia;2004, p331 

    An encyclopedia entry for "gastritis" is presented. It refers to the inflammation of the stomach lining caused by irritation of the tissues. The condition can be classified into acute and chronic. Symptoms of gastritis include discomfort in the upper abdomen, nausea and vomiting. Gastroscopy is...

  • Diagnostic yield of capsule endoscopy for gastric diseases. Kobayashi, Yuka; Watabe, Hirotsugu; Yamada, Atsuo; Hirata, Yoshihiro; Yamaji, Yutaka; Yoshida, Haruhiko; Koike, Kazuhiko // Abdominal Imaging;Feb2012, Vol. 37 Issue 1, p29 

    Background and aim: Capsule endoscopy (CE) for the stomach has not yet been in practical use. Likewise as in colon, CE for colorectal cancer screening, the less invasive nature of CE may be suitable for gastric screening. The aim of this study is to estimate a diagnostic yield of CE for gastric...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics