TITLE

Bile Decompression in Children with Histopathological Evidence of Pre-Existing Liver Cirrhosis

AUTHOR(S)
Jackson, Carl-Christian A.; Wu, Yeming; Chenren, Shi; Somme, Stig; Chwals, Walter J.; Liu, Donald C.
PUB. DATE
September 2002
SOURCE
American Surgeon;Sep2002, Vol. 68 Issue 9, p816
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Although it is agreed upon by most that adequate and timely bile decompression can preserve or even improve existing liver function much debate centers on whether pre-existing liver cirrhosis can also be reversed. To help answer this question we analyzed data on 47 children with choledochal cyst disease (CD) who underwent simultaneous liver biopsy during bile decompression surgery. We collected data on two groups of children with CD spanning two different time periods: January 1985 through November 1994 (Group A) and June 1995 through November 1999 (Group B). In Group A 37 children (16 boys and 21 girls ages 5 days to 10 years) underwent simultaneous liver biopsy during elective definitive surgery for CD. In Group B ten children (five boys and five girls age one month to 7 years) underwent liver biopsy twice: first during initial cyst decompression for acute obstruction and second during elective definitive surgery after resolution of acute disease. Degree of liver cirrhosis was based on a modified World Health Organization classification system (0-IV). In Group A 15/37 (40.5%) had significant liver cirrhosis at time of biopsy (III or IV) with altered liver function in all cases; eight of nine had normal liver function on follow-up, six were lost to follow-up. In Group B seven of ten (70%) had less liver cirrhosis on pathology at second operation with three unchanged; nine of ten (90%) regained normal liver function. We conclude that bile duct obstruction is the main cause of liver cirrhosis in children with CD. Adequate and timely bile decompression can restore normal liver function and even reverse severe cirrhosis.
ACCESSION #
7752138

 

Related Articles

  • Picibanil.  // Reactions Weekly;6/16/2012, Issue 1406, p30 

    The article describes two case reports of male patients in their 40s who experienced a fever and flu-like symptoms after treatment with transcutaneous picibanil for lymphatic cysts.

  • Endoscopic view of Thornwaldt cyst of the nasopharynx. Yanagisawa, Eiji; Yanagisawa, Ken // ENT: Ear, Nose & Throat Journal;Dec1994, Vol. 73 Issue 12, p884 

    Describes the treatment of a patient with a Thornwaldt cyst of the nasopharynx. Medical history of patient; Characteristics of Thornwaldt cysts; Use of magnetic resonance imaging (MRI) to diagnose cyst; Treatment of cyst.

  • Dermoid Cyst of the lateral Neck: A Case Report and Literature Review. Rosen, David; Wirtschafter, Ari; Wilcox, Jr., Thomas O.; Rao, Vijay M. // ENT: Ear, Nose & Throat Journal;Feb1998, Vol. 77 Issue 2, p125 

    Discusses the cases on dermoid cysts. Case of a 30-year-old woman complaining of a lump on the right side of her neck; How the diagnosis was confirmed; Dermoid cysts of the lateral neck; Use of surgical excision to prevent subsequent infection.

  • Endobronchial drainage in case of infected posttraumatic pulmonary pseudocyst: an alternative to surgery? Bulpa, Pierre; Neck, Evelyne; Wispelaere, Jean-François; Michaux, Isabelle; Dive, Alain; Evrard, Patrick // Intensive Care Medicine;Feb2011, Vol. 37 Issue 2, p352 

    A letter to the editor is presented which discusses the case of a 52-year-old man admitted to the intensive care unit (ICU) due to multiple bone fractures who needed urgent splenectomy and endobronchial drainage to treat his infected postraumatic pulmonary pseudocysts.

  • Inflammatory dentigerous cysts of children treated by tooth extraction and decompression—report of four cases. Koǽelj,, V.; Sotošek,, B. // British Dental Journal;12/11/1999, Vol. 187 Issue 11, p587 

    Inflammatory dentigerous cysts are only found in the mixed dentition. The four cases presented here illustrate the uncomplicated behavior of these cysts when properly treated. By extracting the infected primary teeth, opening the cyst and ensuring continuous drainage, it is possible to achieve...

  • Part 6--sebaceous cysts. Sodera, Vij // GP: General Practitioner;11/18/2002, p70 

    Focuses on treatment of cysts in different parts of the body. Description of the disease; Discriminatory features of the disease; Necessity of surgery for removing cyst; Risk of operating facial cyst.

  • Small vocal fold mass causing dysphonia in a professional soprano. Sataloff, Robert Thayer; Baroody, Margaret M. // ENT: Ear, Nose & Throat Journal;Oct1999, Vol. 78 Issue 10, p744 

    Presents a case study on vocal fold cyst. Details on the treatment made to the patient with the cyst; Symptoms of the disease; What the case illustrates.

  • WHAT THEY DIDN'T TELL YOU…MEIBOMIAN CYST.  // GP: General Practitioner;10/21/2002, p52 

    Discusses the method of removing meibomian cyst from the eyes. Use of local anaesthesia; Method of injecting the anaesthetic drops; Way of removing the cyst.

  • Ganglion cyst.  // Mayo Clinic Health Letter;Jul2002, Vol. 20 Issue 7, p7 

    Examines the pathophysiology of ganglion cyst in the U.S. Clinical definition of the cyst; Characteristic site and appearance of a ganglion cyst; Option for the treatment of the cyst. INSET: Another approach..

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics