Diagnosis and Treatment of Intracystic Breast Carcinomas

Markopoulos, Christos; Kouskos, Efstratios; Gogas, Helen; Kakisis, John; Kyriakou, Vasiliki; Gogas, John; Kostakis, Alkis
September 2002
American Surgeon;Sep2002, Vol. 68 Issue 9, p783
Academic Journal
Cystic breast masses are very common in female patients attending breast clinics. Most of them are benign and managed by simple aspiration. We reviewed histology records for the last 12 years to find patients with cystic breast carcinomas and to evaluate special clinical signs that may help to identify patients with this rare entity. Eighteen patients with cystic breast carcinomas were found among 1510 new breast cancer patients (1.19%) who were seen at our Breast Unit during this period. Ten had intracystic papillary carcinoma (0.66% of all breast cancers), seven had cystic degeneration of ductal carcinoma, and one had a mucinous carcinoma. The diagnosis of intracystic papillary carcinoma was based on cyst fluid cytology and breast imaging in most patients and on open breast biopsy in two cases only. The prognosis of our cystic breast carcinoma patients was excellent regardless of the specific histologic type of the tumor. We conclude that cysts in postmenopausal women should be viewed with suspicion. Bloodstained aspirated cyst fluid should be sent for cytology and breast imaging should be carried out in all these cases. Residual mass after cyst aspiration is also an indication for open biopsy.


Related Articles

  • Carcinoma Arising in Microglandular Adenosis of the Breast. Harmon, Maureen; Fuller, Bradbury; Cooper, Kumarasen // International Journal of Surgical Pathology;Oct2001, Vol. 9 Issue 4, p344 

    Discusses the case of carcinoma arising in microglandular adenosis (MGA) of the breast. Detection of the characteristics of MGA using microscopic examination; Identification of foci of intraductal carcinoma within the MGA; Presence of chondroid differentiation on invasive component.

  • Clinicopathological Relationship Between Fibrocystic Disease Complex and Breast Cancer: A Case Report. Rahman, G. A.; Adeniji, K. A. // Journal of Surgical Technique & Case Report;Jan-Jun2010, Vol. 2 Issue 1, p54 

    A letter to the editor is presented which discusses a case report of a 43-year-old woman with intraductal carcinoma or breast cancer developed from fibrocystic disease.

  • breast health basics. Murray, Michael T. // Amazing Wellness;Fall2012, Vol. 4 Issue 5, p40 

    The article provides an answer to a question of what can someone with fibrocystic breast disease do to reduce her risk of developing breast cancer.

  • Induction of atypical ductal hyperplasia in mouse mammary gland organ culture. Mehta, Rajendra G.; Bhat, Krishna P.L.; Hawthorne, Michael E.; Kopelovich, Levy; Mehta, Rajeshwari R.; Christov, Konstantin; Kelloff, Gary J.; Steele, Vernon E.; Pezzuto, John M.; Mehta, R G; Bhat, K P; Hawthorne, M E; Kopelovich, L; Mehta, R R; Christov, K; Kelloff, G J; Steele, V E; Pezzuto, J M // JNCI: Journal of the National Cancer Institute;7/18/2001, Vol. 93 Issue 14, p1103 

    Examines the significance of atypical ductal hyperplasia on the development of ductal carcinoma insitu. Formation of hyperplastic mammary alveolar lesions; Presence of the nonovarian steroid hormones aldosterone and hydrocortisone; Mechanism of progesterone.

  • Carcinoma Arising in Microglandular Adenosis: An Immunohistochemical Analysis of 20 Intraepithelial and Invasive Neoplasms. Koenig, Christopher; Dadmanesh, Farnaz; Bratthauer, Gary L.; Tavassoli, Fattaneh A. // International Journal of Surgical Pathology;Oct2000, Vol. 8 Issue 4, p303 

    Examines the morphologic and immunohistochemical features of 20 case files of the Washington, D.C.-based Armed Forces Institute of Pathology with atypical microglandular adenosis (AMGA) of the breast. Number of cases which contained intraductal carcinoma arising in AMGA; Clinical features;...

  • Fibrocystic breast condition affects more than 60 percent of all women. Wagstaff, Donna // South County Journal;6/27/2012, Vol. 47 Issue 26, pB2 

    The article discusses fibrocystic breast condition, a non-cancerous condition affecting more than 60 percent of women and is most common between the ages of 20 and 50.

  • A Large, Ill-Defined Cystic Breast Mass. Resetkova, Erika; Padula, Anthony; Albarraccin, Constance T.; Sneige, Nour // Archives of Pathology & Laboratory Medicine;Mar2005, Vol. 129 Issue 3, pe79 

    A quiz concerning the pathology of the disease of a 40-year-old African American woman with ill-defined cystic breast mass is presented.

  • Severe Necrotizing Mastopathy Caused by Calciphylaxis Alleviated by Total Parathyroidectomy. Patetsios, Peter; Bernstein, Michael; Kim, Sanghyun; Mushnick, Robert; Alfonso, Antonio // American Surgeon;Nov2000, Vol. 66 Issue 11, p1056 

    Calciphylaxis is a complication caused by secondary hyperparathyroidism in patients with chronic renal failure. These patients may present with clinical findings of ischemic necrosis involving the skin and muscle resulting in subsequent gangrene and vascular calcifications. We report a rare case...

  • Fibroadenomatoid mastopathy-like lesions arising in anogenital mammary-like glands in a 35-year-old man. Fernandez-Aguilar, Sergio; Vazquez-Martín, Angel // International Journal of Colorectal Disease;Nov2009, Vol. 24 Issue 11, p1355 

    A letter to the editor is presented which reports a fibroadenomatoid mastopathy-like lesions arising in anogenital mammary-like glands in a 35-year-old man.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics