KIAA 1096, a Gene on Chromosome 1q, is Amplified and Overexpressed in Bladder Cancer
- Analysis of Her2/neu Overexpression and Amplification in Urothelial Carcinoma of the Bladder Associated with Cox-2 Overexpression. ElMoneim, Hanan Mohamed Abd; Tawfik, Heba Mohamed; El Sherbiny, Yaser Makram; Tawfiek, Ehab Rifat // International Journal of Cancer Research;2011, Vol. 7 Issue 1, p8
No abstract available.
- Erratum to: New code site classification, amplification factors and normalized response spectra based on a worldwide ground-motion database. Pitilakis, Kyriazis; Riga, Evi; Anastasiadis, Anastasios // Bulletin of Earthquake Engineering;Aug2013, Vol. 11 Issue 4, p967
A correction to the article "New code site classification, amplification factors and normalized response spectra based on a worldwide ground-motion database," by Kyriazis Pitilakis and colleagues, published in a 2012 issue of "Bulletin Earthquake Engineering."
- Genetic association with bladder cancer. // British Medical Journal;9/1/1979, Vol. 2 Issue 6189, p514
Examines the association of genetic constitution with bladder cancer. Factors enhancing the risk of bladder cancer; Examination of the ABO antigens and HLA antigens in patients with cell carcinoma of the bladder; Association of ABO blood groups with gastrointestinal cancer.
- p15INK4b in bladder carcinomas: decreased expression in superficial tumours. Le Frère-Belda, M A; Cappellen, D; Daher, A; Gil-Diez-de-Medina, S; Besse, F; Abbou, C C; Thiery, J P; Zafrani, E S; Chopin, D K; Radvanyi, F // British Journal of Cancer;11/15/2001, Vol. 85 Issue 10, p1515
The p15 gene which encodes a cyclin-dependent kinase inhibitor, is located in the 9p21 chromosomal region that is frequently deleted in human bladder transitional cell carcinomas (TCCs). The aim of the present paper is to study the potential involvement of thep15 gene in the evolution of TCCs....
- The hypoxia-inducible genes VEGF and CA9 are differentially regulated in superficial vs invasive bladder cancer. Turner, K.J.; Crew, J.P.; Wykoff, C.C.; Watson, P.H.; Poulsom, R.; Pastorek, J.; Ratcliffe, P.J.; Cranston, D.; Harris, A.L. // British Journal of Cancer;4/22/2002, Vol. 86 Issue 8, p1276
Regulation by hypoxia may underlie the expression of vascular endothelial growth factor in bladder cancer. We have compared the distribution of vascular endothelial growth factor mRNA with a hypoxia marker, carbonic anhydrase 9 (CA IX). vascular endothelial growth factor mRNA was analysed by in...
- Gene expression profiles of bladder cancers: evidence for a striking effect of in vitro cell models on gene patterns. Dangles, V.; Lazar, V.; Validire, P.; Richon, S.; Laville, V. // British Journal of Cancer;4/22/2002, Vol. 86 Issue 8, p1283
In order to assess the effect of in vitro models on the expression of key genes known to be implicated in the development or progression of cancer, we quantified by real-time quantitative PCR the expression of 28 key genes in three bladder cancer tissue specimens and in their derived cell lines,...
- Rapid Assays for Quantitating Cytokine Gene Expression Without Target Amplification. Gonzales, Frank R.; Lois, Augusto; Sewell, Toddy; LaCerte, Carl; Tolley, James; Gaynor, Barbara; Garcia, Eidson; Jazdzewski, Melinda; Olivier, Tammy; Postor, Irene; Trainor, Deirdre // Combinatorial Chemistry & High Throughput Screening;Jun2003, Vol. 6 Issue 4, p293
Many drug discovery efforts are focused on finding candidates that alter gene expression of the cytokines involved in inflammation, allergy, and cell-mediated immunity. Current methods used to evaluate gene expression such as northern blot and RT-PCR are laborious, time-consuming, expensive, and...
- E2F3 is the main target gene of the 6p22 amplicon with high specificity for human bladder cancer. Oeggerli, M.; Schraml, P.; Ruiz, C.; Bloch, M.; Novotny, H.; Mirlacher, M.; Sauter, G.; Simon, R. // Oncogene;10/19/2006, Vol. 25 Issue 49, p6538
Amplification of 6p22 occurs in about 10â€“20% of bladder cancers and is associated with enhanced tumour cell proliferation. Candidate target genes for the 6p22 amplicon include E2F3 and the adjacent gene NM_017774. To clarify which gene is representing the main target, we compared the...
- Altered patterns of MDM2 and TP53 expression in human bladder cancer. Lianes, Pilar; Orlow, Irene // JNCI: Journal of the National Cancer Institute;9/7/94, Vol. 86 Issue 17, p1325
Determines the frequency of MDM2 and TP53 gene abnormalities in bladder tumors. Patient characteristics and tissues; Monoclonal antibodies and immunohistochemistry; Southern blotting for MDM2 amplification; SSCP analysis and DNA sequencing for TP53 mutations; Altered genotype and phenotype of...