TITLE

Chromatographic Determination of Methyl Glyoxal in Blood Plasma as the Test for Glycotoxicity and Accumulation of Glycation End-Products

AUTHOR(S)
Shiryaeva, Yu.; Krylin, V.; Titov, V.
PUB. DATE
May 2012
SOURCE
Bulletin of Experimental Biology & Medicine;May2012, Vol. 153 Issue 1, p114
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We developed a method of measuring methyl glyoxal concentration in blood serum using HPLC with UV detection. Methyl glyoxal concentration was determined in healthy subjects. The method was developed for indirect but reliable measurement of the levels of glycation end-products in patients with diabetes, hyperlipidemia, and cardiovascular pathologies.
ACCESSION #
77057929

 

Related Articles

  • Determination of a-Amanitin in Human Serum by Solid-Phase Extraction Coupled with HPLC-UV. Zhi Zhou; Mm Cao; Liping Zhou; Xiongjun Zuo; Youwen Tang // LC-GC North America;Aug2011, Vol. 29 Issue 8, p672 

    The purpose of this study is to develop a fast and sensitive method for the determination of a-amanitin, toxic peptides of amanitin mushrooms, in human serum by solid-phase extraction (SPE) coupled with high performance liquid chromatography with UV detection.

  • DESARROLLO Y VALIDACIÓN DE UN MÉTODO ANALÍTICO PARA LA DETERMINACIÓN DE CIPROFLOXACINA EN SUERO POR CROMATOGRAFÍA LIQUIDA DE ALTA PRECISIÓN CON DETECCIÓN ULTRAVIOLETA. FALQUEZ MANOTAS, ANA; SARMIENTO RUBIANO, LUZ // Archivos de Medicina (1657-320X);jul-dic2013, Vol. 13 Issue 2, p119 

    Objective: To develop a rapid and simple method for Ciprofloxacin determination in samples of whey to be used in pharmacokinetic studies. Ciprofloxacin is an antibiotic that belongs to the group of the fluoroquinolone, commonly used in Colombia with an extensive antibacterial spectrum. Several...

  • ESTIMATION OF URINARY ALBUMIN IN DIABETIC PATIENTS BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY. AHMED, SAGHEER; AHSAN, SHAHID; NAUMAN, KIRAN; AHMED, SYED DANISH HASEEN; HAQUE, MUHAMMAD SAIFUL; KRAIRA, KHEMOMAL A. // Medical Channel;Jan-Mar2013, Vol. 19 Issue 1, p65 

    Background: Albumin appears in urine in two forms, immunoreactive and immunounreactive. Albuminuria estimation by immunoassay techniques detected only immunoreactive albumin in the urine of diabetic patients. Methods: High performance liquid chromatography (HPLC) was used to measure albuminuria...

  • EVALUATION OF SERUM HIGH SENSITIVITY C - REACTIVE PROTEIN (hs-CRP) IN TYPE-2 DIABETIC PATIENT. Haque, A. K. M. Fazlul; Ekram, A. R. M. Saifuddin; Islam, Quazi Tarikul; Jahan, Md. Sarwar; Haque, Md. Zahirul // Journal of Medicine;Jan2010, Vol. 11 Issue 1, p20 

    Type-2 diabetes may remain in subclinical form for years before diagnosis. This quiescence of type-2 diabetes is a great concern for health care providers. The earliest change of the type-2 diabetes is the insulin resistance, which is associated with the increased macrovascular risk due to...

  • Determination of Repaglinide in Pharmaceutical Formulations by RP-HPLC Method. Rani, A. Prameela; Sekaran, C. Bala; Archana, N.; Teja, P. Siva; Aruna, B. // Journal of Applied Sciences Research;Oct2009, Vol. 5 Issue 10, p1500 

    A new Reverse phase high performance liquid chromatographic (RP-HPLC) method was developed and validated for the determination of repaglinid e in pharmaceutical formulations. Optimum separation was achieved in 12 minutes us ing C18 column (250 mm × 4.6 mm, i.d., particle size 5 mm), and...

  • Association between Sex Differences and the Pharmacokinetics of Repaglinide among a Malaysian Population. Bakar, Ruzilawati Abu; Wahab, Mohd Suhaimi Ab; Ahmad, Imran; Gan Siew Hua // Pharmacology & Pharmacy;Oct2011, Vol. 2 Issue 4, p332 

    This study was conducted to evaluate the effect of sex differences on the pharmacokinetics of repaglinide in healthy subjects. One hundred twenty one healthy volunteers (61 male and 60 female; aged 18 - 50 years) were included in the study. Subjects were administered a single 4-mg repaglinide...

  • Simple and Reliable HPLC Method for the Monitoring of Methotrexate in Osteosarcoma Patients. Begas, Elias; Papandreou, Christos; Tsakalof, Andreas; Daliani, Danai; Papatsibas, George; Asprodini, Eftihia // Journal of Chromatographic Science;Aug2014, Vol. 52 Issue 7, p590 

    Methotrexate (MTX) is a dihydrofolate reductase inhibitor that is used for the treatment of tumors and autoimmune diseases. Several automated binding assays are used in clinical practice and numerous chromatographic methods have been developed toward higher specificity and sensitivity. In the...

  • Rapid HPLC Method for Determination of Parachloroaniline in Chlorhexidine Antiseptic Agent in Mouthrinses, Ophthalmic and Skin Solution. Nicolay, Alain; Wolff, Estelle; Vergnes, Marie-France; Kaloustian, Jacques; Portugal, Henri // American Journal of Analytical Chemistry;Aug2011, Vol. 2 Issue 4, p422 

    We described a simple and rapid method to quantify simultaneously chlorhexidine (CHD) and its major metabolite, para Chloroaniline (pCA) by HPLC with UV detection without the additional need of mobile-phase amine modifiers or ion-pairing reagents, with good resolution between pCA and CHD,...

  • Quantification of pendimethalin in soil and garlic samples by microwave-assisted solvent extraction and HPLC method. Shah, Jasmin; Rasul Jan, M.; Shehzad, Farhat-un-nisa; Ara, Behisht // Environmental Monitoring & Assessment;Apr2011, Vol. 175 Issue 1-4, p103 

    method for the residual pendimethalin in soil and vegetable samples was developed. The method is based on extraction of pendimethalin from samples using microwave-assisted solvent extraction (MASE) with acetone, ethanol, and water as extraction solvent. Extracted pendimethalin samples were...

Share

Read the Article

Courtesy of NEW JERSEY STATE LIBRARY

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics