Dissecting genomic regulatory elements in vivo

Haberle, Vanja; Lenhard, Boris
June 2012
Nature Biotechnology;Jun2012, Vol. 30 Issue 6, p504
Academic Journal
The article presents information on controlling gene expression by promoter or enhancer. A focus is on the in vivo investigation of the regulatory-element variants which is less tedious than the earlier labor-intensive tasks of molecular biology. The new throughput approach is based on genome-wide determination of the interactions of protein-deoxyribonucleic acid (DNA). Several papers are also discussed based on this process.


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