TITLE

Preoperative Treatment Does Not Improve the Therapeutic Results of Abdominosacral Amputation of the Rectum

AUTHOR(S)
Bębenek, Marek; Tupikowski, Wiesław; Cisarż, Karol; Balcerzak, Alicja; Wojciechowski, Leszek; Stankowska, Anna; Tarkowski, Radosław
PUB. DATE
July 2012
SOURCE
World Journal of Surgery;Jul2012, Vol. 36 Issue 7, p1686
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: This study reviewed the impact of preoperative chemoradiotherapy/short-term radiotherapy on abdominosacral amputations of the rectum (ASAR) for the treatment of low-rectum cancers in terms of postoperative morbidity, local recurrence rates, and survival. Methods: A total of 198 patients with stage II and III tumors located within 6 cm of the anorectal junction underwent ASAR between 1998 and 2008 and were selected for further analysis. Patients were compared according to the following groups: those who had surgery only (Group A) and those who had preoperative chemoradiotherapy/short-term radiotherapy (Group B). Results: There were 44 and 154 patients in Groups A and B, respectively, including 135 males. The median age of the subjects was 63 years (range = 35-88). The median follow-up period was 81 months (range = 23-138). Neither the local recurrence rates (6.8% in Group A vs. 4.6% in Group B, p = 0.544) nor the 5-year relative survival rates (72.4% in Group A vs. 69.3% in Group B, p = 0.127) differed significantly between the groups. Conclusion: Preoperative therapy in low-rectum cancer does not improve the therapeutic results of ASAR.
ACCESSION #
76350200

 

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