Prothrombin index slope is an early prognostic marker in patients with severe acute liver diseases

Nalpas, Bertrand; Francoz, Claire; Ichaï, Philippe; Jamot, Laure; Faivre, Jamila; Lemoinne, Sara; Samuel, Didier; Durand, François; Bernuau, Jacques; Bréchot, Christian; Amouyal, Paul; Amouyal, Gilles
July 2012
Gut;Jul2012, Vol. 61 Issue 7, p1198
Academic Journal
The article presents information on the prognostic makers and their requirement in acute liver disease with reference to the slope in the prothrombin index. The Impact of the serum levels of the von Willebrand factor results in the worsening of the patients requiring liver transplantation due to the cirrhosis. Information on the impact of the prothrombin index slope on the requirement of liver transplantation of patients suffering from cirrhosis is also presented.


Related Articles

  • Alcoholics and Liver Transplantation. Cohen, Carl; Benjamin, Martin // JAMA: Journal of the American Medical Association;3/13/91, Vol. 265 Issue 10, p1299 

    Presents arguments underlying a widespread unwillingness to consider patients with alcoholic cirrhosis of the liver as candidates for transplantation. Reasons for precluding alcoholics as candidates for liver transplantation; Moral and medical argument on the issue; Selection process of liver...

  • Liver Transplants.  // American Medical Association Family Medical Guide;2004, p790 

    The article discusses topics on liver transplant. In the transplantation of the liver, about 80 to 90 percent of people survive liver transplant surgery. Transplants are usually recommended for people whose liver has been severely damaged by chronic cirrhosis. Moreover, Transplants can be...

  • Thrombotic microangiopathy following organ transplantation. Ruggenenti, Piero // Kidney International;May2003, Vol. 63 Issue 5, p1959 

    Responds to Phuong-Thu T. Pham and colleagues' comments on the authors' article regarding thrombotic microangiopathy (TMA) following organ transplantation. Forms of TMA; Criteria for administering plasma therapy to patients with TMA; Deficiency of von Willebrand factor-cleaving protease activity.

  • Thrombotic microangiopathy following organ transplantation. Pham, Phuong-Thu T.; Pham, Phuong-Chi T.; Wilkinson, Alan H. // Kidney International;May2003, Vol. 63 Issue 5, p1959 

    Comments on Piero Ruggenenti's article regarding thrombotic microangiopathy (TMA) following organ transplantation. Deficiency of von Willebrand factor-cleaving protease activity; Efficacy of plasma therapy against TMA.

  • Impaired activity of plasma von Willebrand factor-cleaving protease may predict the occurrence of hepatic veno-occlusive disease after stem cell transplantation. Park, Y-D; Yoshioka, A; Kawa, K; Ishizashi, H; Yagi, H; Yamamoto, Y; Matsumoto, M; Fujimura, Y // Bone Marrow Transplantation;5/1/2002, Vol. 29 Issue 9, p789 

    Provides information on a study that investigated the correlation between plasma von Willebrand factor-cleaving protease activity and unusually large von Willebrand factor multimers in patients who received stem cell transplantation. Details on the patients and methodologies used; Results and...

  • Features of HCV recurrence in patients with HCV - related cirrhosis after liver transplantation and its antiviral and immunomodulatory therapies. JIAO Jian; WANG Jiangbin // Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi;2014, Vol. 30 Issue 1, p14 

    The best choice of treatment for patients with HCv-related cirrhosis may be liver transplantation once liver decompensation occurs. Immunoregulatory drugs, especially immunosuppressants, may be a main causative factor for accelerated HCv recurrence after liver transplantation. How to control HCv...

  • Cyclosporin A in Nontransplant-Related Liver Disease. Minuk, G. Y. // American Journal of Gastroenterology;Nov1989, Vol. 84 Issue 11, p1345 

    Cyclosporin A is a potent immunosuppressive agent that has revolutionized the care of organ transplant recipients. Recently, the use of cyclosporin A has been extended beyond the transplant setting to include certain disorders that are thought to be immunologically mediated. This review focuses...

  • Corticospinal involvement in patients with a portosystemic shunt due to liver cirrhosis. Nardone, Raffaele; Buratti, Thomas; Oliviero, Antonio; Lochmann, Andreas; Tezzon, Frediano // Journal of Neurology;Jan2006, Vol. 253 Issue 1, p81 

    Hepatic myelopathy (HM) is a rare complication of chronic liver diseases usually associated with a portosystemic shunt, causing a progressive spastic paraparesis, and is likely to be overlooked. Thirteen patients with liver cirrhosis associated with surgical or spontaneous portosystemic shunts...

  • liver transplant. Peters, Michael // BMA A-Z Family Medical Encyclopedia;2004, p473 

    An encyclopedia entry for "liver transplant" is presented. It refers to a procedure that replaces a diseases liver with a healthy liver coming from a donor. It is noted that the usual donor is a dead person but there are times when part of the liver is obtained from a living relative of the...


Read the Article


Sign out of this library

Other Topics