TITLE

Cutaneous microdialysis in the rat: insertion trauma studied by ultrasound imaging

AUTHOR(S)
Groth, Lotte; Jørgensen, Askel; Serup, Jørgen
PUB. DATE
April 1998
SOURCE
Acta Dermato-Venereologica;4/20/98, Vol. 78 Issue 1, p10
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Microdialysis is a method by which compounds can be studied in the extracellular space in skin, in vivo. The microdialysis probe is inserted in the dermis using a guide cannula. It is expected that intradermal oedema associated with insertion trauma as well as the probe depth can influence the results of microdialysis studies. The aim of the present study was to assess the effects of insertion trauma and, additionally, the probe depth by ultrasound. High-frequency (20 MHz) ultrasound is a non-invasive method for measuring the thickness and echostructure of skin. Hairless rats were anaesthetized with either halothane (n = 7) or pentobarbital sodium (n = 6). The insertion of the microdialysis probe resulted in a 38% relative increase in skin thickness. At 120 min the skin thickness had not reached the pre-insertion value. Thus, significant skin thickening, representing traumatic oedema, developed due to insertion of the microdialysis probe in the skin. The microdialysis probe could be inserted reproducibly in the lower dermis.
ACCESSION #
7615816

 

Related Articles

  • Ultraschallgestützte zentrale Venenpunktion bei Erwachsenen und Kindern. Scheiermann, P.; Seeger, F.H.; Breitkreutz, R. // Anaesthesist;Jan2010, Vol. 59 Issue 1, p53 

    Central venous line placement is a standard procedure in critical care and peri-operative medicine. This procedure can be associated with severe complications. In contrast to the landmark technique, ultrasound-guided punctures can significantly reduce the rate of complications. Patients with a...

  • Salvage of a radiocephalic fistula by the palmar arch. Knops, Noël; Beek, Erik // NDT Plus;Oct2008, Vol. 1 Issue 5, p326 

    We present a child with mild problems during haemodialysis due to stenosis of the proximal radial artery of his radiocephalic fistula. However, his problems spontaneously subsided. Follow-up sonography revealed arterial occlusion proximal to the fistula with retrograde flow in the distal...

  • Parameters derived by ultrasonic myocardial characterization in dialysis patients are associated with mortality. Pizzarelli, Francesco; Dattolo, Pietro; Ferdeghini, Ezio Maria; Aurora Morales, Maria; Morales, Maria Aurora // Kidney International;Sep2005, Vol. 68 Issue 3, p1320 

    Background: Autopsy studies have shown that hypertrophic hearts of uremic patients have peculiar characteristics. Changes in tissue structure are detectable by ultrasound as changes in echo reflectivity. Methods: We studied 96 dialysis patients, 18 hypertensive subjects...

  • Regular ultrasonographic screening significantly prolongs patency of PTFE grafts. Malik, Jan; Slavikova, Marcela; Svobodova, Jaroslava; Tuka, Vladimir // Kidney International;Apr2005, Vol. 67 Issue 4, p1554 

    Regular ultrasonographic screening significantly prolongs patency of PTFE grafts.Background.Polytetrafluoroethylene (PTFE) dialysis grafts have considerably shorter patency than native arteriovenous fistulas, despite the use of a complex of screening monitoring methods (venous pressure, access...

  • Percutaneous US-guided RF thermal ablation for malignant renal tumors: preliminary results in 13 patients. Veltri, Andrea; De Fazio, Giuseppina; Malfitana, Valeria; Isolato, Giuseppe; Fontana, Dario; Tizzani, Alessandro; Gandini, Giovanni // European Radiology;Dec2004, Vol. 14 Issue 12, p2303 

    Minimally invasive treatment for small renal cell carcinoma (RCC) can be necessary in selected patients and, anyway, is desirable. In situ ablation techniques, including RFA, have been developed. The aim of this study is to evaluate the feasibility, safety and short-term local effectiveness of...

  • Dual Kidney Transplantation: Case Report.  // Collegium Antropologicum;Jun2010, Vol. 34 Issue 2, p697 

    No abstract available.

  • Skeletal Status in Children, Adolescents and Young Adults with End-Stage Renal Failure Treated with Hemo- or Peritoneal Dialysis. Pluskiewicz, W.; Adamczyk, P.; Drozdzowska, B.; Szprynger, K.; Szczepanska, M.; Halaba, Z.; Karasek, D. // Osteoporosis International;May2002, Vol. 13 Issue 5, p353 

    : The skeletal status in 30 children, adolescents and young adults (18 females, 12 males) with end-stage renal failure (ESRF) aged 9-23 years (mean 15.8 ± 3.6 years) was evaluated using measurements of bone mineral density (BMD, g/cm2) at the spine and total body (TB) (Lunar DPX-L, USA),...

  • Guidewire fragmentation complicating hemodialysis catheter insertion. Haldar, R.; Samanta, S. // Indian Journal of Nephrology;Nov/Dec2013, Vol. 23 Issue 6, p468 

    The article presents the case of a 49-year-old female weighing 96 kilograms and was a renal recipient patient with the chronic graft rejection and imminent sepsis. The patient was posted for hemodialysis. The nephrologists attempted two blind anatomical landmark in the right and left internal...

  • Prevalence of nephrolithiasis in polycystic kidney disease. Idrizi, Alma; Barbullushi, Myftar; Gjata, Margarita; Koroshi, Alketa; Roshi, Enver; Backa, Teuta; Kodra, Sulejman; Thereska, Nestor // Central European Journal of Medicine;Aug2011, Vol. 6 Issue 4, p497 

    We aim to define the prevalence of nephrolithiasis, the impact of anatomic and metabolic factors to stone formation and prognosis of patients with autosomal dominant polycystic kidney disease in Albania. We included 200 patients with autosomal dominant polycystic kidney from 2002 to 2009. The...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics