TITLE

Real-time confocal imaging of trafficking of nestin-expressing multipotent stem cells in mouse whiskers in long-term 3-D histoculture

AUTHOR(S)
Duong, Jennifer; Mii, Sumiyuki; Uchugonova, Aisada; Liu, Fang; Moossa, A.; Hoffman, Robert
PUB. DATE
May 2012
SOURCE
In Vitro Cellular & Developmental Biology Animal;May2012, Vol. 48 Issue 5, p301
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
No abstract available.
ACCESSION #
76141798

 

Related Articles

  • Extensive Hair-Shaft Elongation by Isolated Mouse Whisker Follicles in Very Long-Term Gelfoam® Histoculture. Cao, Wenluo; Li, Lingna; Mii, Sumiyuki; Amoh, Yasuyuki; Liu, Fang; Hoffman, Robert M. // PLoS ONE;09/30/2015, Vol. 10 Issue 10, p1 

    We have previously studied mouse whisker follicles in Gelfoam® histoculture to determine the role of nestin-expressing plutipotent stem cells, located within the follicle, in the growth of the follicular sensory nerve. Long-term Gelfoam® whisker histoculture enabled hair follicle...

  • Nestin-Expressing Stem Cells Promote Nerve Growth in Long-Term 3-Dimensional Gelfoam®-Supported Histoculture. Mii, Sumiyuki; Uehara, Fuminari; Yano, Shuya; Tran, Benjamin; Miwa, Shinji; Hiroshima, Yukihiro; Amoh, Yasuyuki; Katsuoka, Kensei; Hoffman, Robert M. // PLoS ONE;Jun2013, Vol. 8 Issue 6, p1 

    We have previously reported that hair follicles contain multipotent stem cells which express nestin. The nestin-expressing cells form the hair follicle sensory nerve. In vitro, the nestin-expressing hair follicle cells can differentiate into neurons, Schwann cells, and other cell types. In the...

  • Long-Term Extensive Ectopic Hair Growth on the Spinal Cord of Mice from Transplanted Whisker Follicles. Cao, Wenluo; Li, Lingna; Mii, Sumiyuki; Amoh, Yasuyuki; Liu, Fang; Hoffman, Robert M. // PLoS ONE;8/5/2015, Vol. 10 Issue 8, p1 

    We have previously demonstrated that hair follicles contain nestin-expressing pluripotent stem cells that can effect nerve and spinal cord repair upon transplantation. In the present study, isolated whisker follicles from nestin-driven green fluorescent protein (ND-GFP) mice were histocultured...

  • Stress and glucocorticoids promote oligodendrogenesis in the adult hippocampus. Chetty, S; Friedman, A R; Taravosh-Lahn, K; Kirby, E D; Mirescu, C; Guo, F; Krupik, D; Nicholas, A; Geraghty, A C; Krishnamurthy, A; Tsai, M-K; Covarrubias, D; Wong, A T; Francis, D D; Sapolsky, R M; Palmer, T D; Pleasure, D; Kaufer, D // Molecular Psychiatry;Dec2014, Vol. 19 Issue 12, p1275 

    Stress can exert long-lasting changes on the brain that contribute to vulnerability to mental illness, yet mechanisms underlying this long-term vulnerability are not well understood. We hypothesized that stress may alter the production of oligodendrocytes in the adult brain, providing a cellular...

  • A population of Nestin-expressing progenitors in the cerebellum exhibits increased tumorigenicity. Li, Peng; Du, Fang; Yuelling, Larra W; Lin, Tiffany; Muradimova, Renata E; Tricarico, Rossella; Wang, Jun; Enikolopov, Grigori; Bellacosa, Alfonso; Wechsler-Reya, Robert J; Yang, Zeng-jie // Nature Neuroscience;Dec2013, Vol. 16 Issue 12, p1737 

    It is generally believed that cerebellar granule neurons originate exclusively from granule neuron precursors (GNPs) in the external germinal layer (EGL). Here we identified a rare population of neuronal progenitors in mouse developing cerebellum that expresses Nestin. Although Nestin is widely...

  • A dermal niche for multipotent adult skin-derived precursor cells. Fernandes, Karl J. L.; McKenzie, Ian A.; Mill, Pleasantine; Smith, Kristen M.; Akhavan, Mahnaz; Barnabé-Heider, Fanie; Biernaskie, Jeff; Junek, Adrienne; Kobayashi, Nao R.; Toma, Jean G.; Kaplan, David R.; Labosky, Patricia A.; Rafuse, Victor; Chi-Chung Hui; Miller, Freda D. // Nature Cell Biology;Nov2004, Vol. 6 Issue 11, p1082 

    A fundamental question in stem cell research is whether cultured multipotent adult stem cells represent endogenous multipotent precursor cells. Here we address this question, focusing on SKPs, a cultured adult stem cell from the dermis that generates both neural and mesodermal progeny. We show...

  • Molecular Imaging and Stem Cell Research. Yoon-Young Jang; Zhaohui Ye; Linzhao Cheng // Molecular Imaging;Jan/Feb2012, Vol. 11 Issue 1, p111 

    During the last decade, there has been enormous progress in understanding both multipotent stem cells such as hematopoietic stem cells and pluripotent stem cells such as embryonic stem cells and induced pluripotent stem cells. However, it has been challenging to study developmental potentials of...

  • Mending a broken heart. Fletcher, Liz // Nature Biotechnology;May2001, Vol. 19 Issue 5, p421 

    Focuses on two research performed at Columbia University in New York, to repair the damage to the heart inflicted by a heart attack by cell transplantation. Effect of angioblast stem cells derived from bone marrow on endothelial cell lining blood vessels; Method of injecting multipotent cells...

  • Real-time imaging of bHLH transcription factors reveals their dynamic control in the multipotency and fate choice of neural stem cells. Itaru Imayoshi; Fumiyoshi Ishidate; Ryoichiro Kageyama // Frontiers in Cellular Neuroscience;Aug2015, Vol. 9, p1 

    The basic-helix-loop-helix (bHLH) transcription factors Ascl1/Mash1, Hes1, and Olig2 regulate the fate choice of neurons, astrocytes, and oligodendrocytes, respectively; however, these factors are coexpressed in self-renewing multipotent neural stem cells (NSCs) even before cell fate...

  • Derivation of engraftable skeletal myoblasts from human embryonic stem cells. Barberi, Tiziano; Bradbury, Michelle; Dincer, Zehra; Panagiotakos, Georgia; Socci, Nicholas D; Studer, Lorenz // Nature Medicine;May2007, Vol. 13 Issue 5, p642 

    Human embryonic stem cells (hESCs) are a promising source for cell therapy in degenerative diseases. A key step in establishing the medical potential of hESCs is the development of techniques for the conversion of hESCs into tissue-restricted precursors suitable for transplantation. We recently...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics