TITLE

Transplantation: Handling complement for transplant success

AUTHOR(S)
Bordon, Yvonne
PUB. DATE
June 2012
SOURCE
Nature Reviews Immunology;Jun2012, Vol. 12 Issue 6, p401
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses a study entitled "Antigen-presenting cell-derived complement modulates graft-versus-host disease," by W. H. Kwan and colleagues, which shows that total-body irradiation (TBI) causes host dendritic cells (DCs) to upregulate the complement components C3, C5a, factor B and factor D, and to downregulate CD55, a negative regulator of the complement cascade.
ACCESSION #
75913566

 

Related Articles

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics