TITLE

Molecular Detection of qnrA, qnrB and qnrS Resistance Genes axnong Salmonella spp. in Iran

AUTHOR(S)
Saboohi, R.; Siadat, S. D.; Aghasadeghi, M. R.; Razavi, M. R.; Rajaei, B.; Sepehri Rad, N.; Moshiri, A.; Mousavi, S. F.; Javadian, S.; Kave, K.; Dashtbani-Roozbehani, A.; Sadat, S. M.; Nejad, S. Gerayesh; Kashanizadeh, N.
PUB. DATE
February 2012
SOURCE
Current Research in Bacteriology;2012, Vol. 5 Issue 1, p24
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Eighty five isolates of Salmonella spp. collected from different provinces of lran during the years 2008 to 2010, vvere screened for the qnrA, qnrB and qnrS genes by PCR. PCR assays detected 22 of 85 (25.8%) Salmonella spp. isolates carried the qnrA gene, 1 (1.17%) of 85 isolates harbored the qnrB and 1 (1.17%) of 85 isolates contained the qnrS gene and 1 isolate carried all the three qnrA, qnrB and qnrS genes. Resistance to quinolones and fluoroquinolones by these genes has been confirmed. Antimicrobial susceptibility patterns of isolates vvere as follovv: 49 (57.6%) isolates exhibited resistance to nalidixic acid and none to ciprofloxacin. As expected, l\/llC assay confirmed these results. Having detected the qnr genes and consequently resistance to quinolones and fluoroquinolones in Salmonella isolates indicated that qnr genes are disseminating among Salmonella serovars.
ACCESSION #
75899628

 

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