Review: Inhaled corticosteroids for asthma or chronic obstructive pulmonary disease do not increase bone loss

Greenstone, Michael
September 2002
ACP Journal Club;Sep/Oct2002, Vol. 137 Issue 2, p63
Academic Journal
Presents a study that investigated the effect of inhaled corticosteroids on bone loss in patients with asthma or chronic obstructive pulmonary disease. Information on data sources and study selection; Comparison of vertebral fracture outcomes at six weeks to three years; Analysis of bone mineral density and bio-chemical markers.


Related Articles

  • Therapeutics. Inhaled corticosteroids for people with chronic obstructive pulmonary disease are associated with an increased risk of fracture. Putcha, Nirupama; Drummond, M. Bradley // Evidence Based Medicine;Jun2012, Vol. 17 Issue 3, p90 

    The authors comment on the study "Risk of fractures with inhaled corticosteroids in COPD: systematic review and meta-analysis of randomised controlled trials and observational studies," by Y. K. Loke, R. Cavallazzi, and S. Singh, in the August 2011 issue of "Thorax." They note the relationship...

  • Inhaled Corticosteroids, Bone Mineral Density and Fracture in Older People. Hubbard, Richard; Tattersfield, Anne // Drugs & Aging;2004, Vol. 21 Issue 10, p631 

    The efficacy of inhaled corticosteroids in the treatment of asthma has been firmly established in a variety of settings. The majority of asthma management plans now recommend the use of inhaled corticosteroids at an early stage. This means that most patients with asthma will be prescribed an...

  • Inhaled corticosteroids don't increase nonvertebral fracture risk.  // Reactions Weekly;1/29/2005, Issue 1036, p5 

    Presents the results of a study on the association between the use of inhaled corticosteroids and the risk of nonvertebral fractures in patients with chronic obstructive pulmonary disease in the U.S. Comparison between patients with a treated nonvertebral fracture and patients who served as the...

  • Effect of Inhaled Glucocorticoids and β2 Agonists on Vertebral Fracture Risk in COPD Patients: The EOLO Study. Gonnelli, S.; Caffarelli, C.; Maggi, S.; Guglielmi, G.; Siviero, P.; Rossi, S.; Crepaldi, G.; Nuti, R. // Calcified Tissue International;Aug2010, Vol. 87 Issue 2, p137 

    Although inhaled glucocorticoids (GCs) and β2 agonists are being more frequently prescribed in the management of chronic obstructive pulmonary disease (COPD), their role in the impairment of bone status and in fracture risk remains controversial. This study aimed to evaluate whether the dose...

  • Benefits and Risks of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease. Bonay, M.; Bancal, C.; Crestani, B. // Drug Safety;2002, Vol. 25 Issue 1, p57 

    Inhaled corticosteroids have a proven benefit in the management of asthma, but until recently, their efficacy in non-asthmatic, smoking-related chronic obstructive pulmonary disease (COPD) was not evidence-based. Airway inflammation in COPD differs from inflammation in asthma. Some studies have...

  • Inhaled corticosteroids and COPD exacerbations. Kuritzky, Louis // Internal Medicine Alert;3/29/2010, Vol. 32 Issue 6, p48 

    The article reports on the effectiveness of inhaled corticosteroids (ICS) in treating acute exacerbations of chronic obstructive pulmonary disease (AC-COPD).

  • High-dose steroids cut COPD deaths. Polak, Monika // GP: General Practitioner;2/3/2003, p17 

    Reports on a study published in the 'European Respiratory Journal' stating that treating patients with medium and high dose of inhaled corticosteroids after discharge from hospital from chronic obstructive pulmonary disease (COPD) have a lower risk of deaths. Doses of steroids for patients with...

  • Discontinuing Inhaled Steroids in COPD Patients. Carter, Chuck // American Family Physician;4/15/2003, Vol. 67 Issue 8, p1803 

    Discusses the study 'Effect of Discontinuation of Inhaled Corticosteroids in Patients With Chronic Obstructive Pulmonary Disease,' by P. Van der Valk et al., from the November 15, 2002 issue of the 'American Journal of Respiratory and Critical Care Medicine.'

  • Combination therapy in COPD benefits patients.  // Practice Nurse;3/14/2003, Vol. 25 Issue 5, p19 

    Presents a study about the significance of combining an inhaled long-acting beta[sub2]-agonist with an inhaled corticosteroid to patients with chronic obstructive pulmonary disease. Reduction in exacerbations in the combined group compared with reductions in the monotherapy groups; Difference...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics