TITLE

Synthesis of Some Quinolone Derivatives with Possible Local Anaesthetics Activities

AUTHOR(S)
Gupta, Ajay Kumar; Agarwal, A. K.; Mehra, S. C.
PUB. DATE
May 2012
SOURCE
Asian Journal of Chemistry;2012, Vol. 24 Issue 5, p2359
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Various new 7-[N-substituted acetyl amino]-2-methyl-4-quinolone were systheized by condensing 2-methyl-7-amino-4-quinolone with chloroacetyl chloride to get 2-methyl-7-chloroacetyl amino-4-quinolone, which on further reaction with various secondary amines to afford the required derivatives. The compounds were tested for their local anesthetic activity.
ACCESSION #
75192666

 

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