Drug interactions of antihypertensive agents

Opie, L. H.
April 2012
South African Family Practice;Apr/May2012, Vol. 54 Issue 2, pS23
Academic Journal
The article discusses the drug interactions of various classes of antihypertensive drugs. It notes the vulnerability of metoprolol, carvedilol and propranol to hepatic interactions. Both statins and beta blockers interact with verapamil. Information on the mechanism of action of nifedipine. An interaction between a diuretic and antiarrhythmic agent can lead to torsades. It cites hyperkalaemia as major risk posed by angiotensin converting enzyme (ACE) inhibitor and spironolactone co-therapy.


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