TITLE

Opinion: Anti-oestrogenic prevention of breast cancer — the make or break point

AUTHOR(S)
Powles, Trevor J.
PUB. DATE
October 2002
SOURCE
Nature Reviews Cancer;Oct2002, Vol. 2 Issue 10, p787
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Clinical trials have shown that giving anti-oestrogens to healthy women can reduce the early incidence of breast cancer by ∼40%. However, the large numbers of women treated, compared with the few who get breast cancer, together with the not insignificant toxicity and the unknown long-term clinical benefits and risks, makes this strategy of prevention versus treatment precarious. So how can we improve the odds for the successful use of endocrine chemoprevention?
ACCESSION #
7502883

 

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