Peripheral T-Cell Lymphoma of Cervical Spine

Foot-Juh Lian; Wen-Chiuan Tsai; Cheng-Ta Hsieh
February 2012
Surgical Science;Feb2012, Vol. 3 Issue 2, p96
Academic Journal
Peripheral T-cell lymphoma is a rather uncommon non-Hodgkin's lymphoma with the initial manifestation of spinal cord compression. Herein, we reported a 74-year-old woman with sustained neck pain radiating into the right shoulder and arm and weakness of the right upper extremity. A mass that had invaded the C5 and C6 vertebral bodies, causing a kyphotic curvature and compressing the spinal cord, was discovered with magnetic resonance imaging. The patient then underwent anterior corpectomy at C5 and C6, and reconstruction with a titanic rod and bone cement. The pathology confirmed a diagnosis of peripheral T-cell lymphoma after serial H & E and immunohistochemical staining. She recovered well from her profound neurological deficit. Both chemotherapy and radiotherapy were used postoperatively. Surgical intervention is indicated in these cases to decompress the cord, remove the majority of the tumor mass, stabilize the spine and obtain tissue for pathological diagnosis.


Related Articles

  • When is PET not useful in the assessment of lymphoma? O'Doherty, Michael J.; Barrington, Sally F. // European Journal of Nuclear Medicine & Molecular Imaging;2003, Vol. 30 Issue 9, p1203 

    The article focuses on the use of positron emission tomography in the assessment of lymphoma. Cure rates of greater than 80% are achieved overall in patients with Hodgkin's disease, with greater than 90% cure in favourable disease and 65% cure in less favourable disease. Therapy is tailored...

  • T-cell / histiocyte-rich B cell lymphoma mimicking Hodgkin's lymphoma. Majhi, U.; Shirley, S.; Murhekar, K. M. // Indian Journal of Cancer;Jan-Mar2010, Vol. 47 Issue 1, p70 

    The article presents case studies of T-cell/Histiocyte-rich large B-cell lymphoma (THRBCL) which are diagnosed for three years. It mentions that the cases were between ages 17 and 57 years. It is stated that the cases depict a small percentage of tumor cells of THRBCL depicting features that...

  • Extranodal nasal-type NK/T-cell lymphoma: Computed tomography findings of head and neck involvement. Jinna Kim; Eung Yeop Kim; Seung-Koo Lee; Dong Ik Kim; Chang-Hoon Kim; Se-Heon Kim; Eun Chang Choi // Acta Radiologica;Feb2010, Vol. 51 Issue 2, p164 

    Background: Extranodal nasal-type natural killer (NK)/T-cell lymphoma (NKTL) is a rare, but distinct clinical entity in Asian populations. However, it is not uncommon for NKTL to be belatedly or postoperatively diagnosed because radiologists are not familiar with its radiological features....

  • Non-Hodgkin Lymphoma. Fox, Christopher; Mead, Adam; Sellar, Rob // Current Medical Literature: Leukemia & Lymphoma;2012, Vol. 20 Issue 1, p26 

    The article provides information on studies on non-Hodgkin lymphoma published in medical journals in 2011. M. Yamaguchi et al provided a phase ll study of a novel, non-cross resistant regimen called SMILE chemotherapy for newly diagnosed stage lV, relapsed or refractory extranodal natural...

  • Hodgkin Lymphoma and Cutaneous T-Cell Lymphoma Sharing the PCM1-JAK2 Fusion and a Common T-Cell Clone. Riedlinger, Gregory M.; Chojecki, Aleksander; Aviv, Hana; Weissmann, David; Joshi, Sonali; Murphy, Susan M.; Hirshfield, Kim M.; Ganesan, Shridar // JCO Precision Oncology;6/19/2019, Vol. 3, p1 

    A case study of a patient who had a history of red, blotchy, nonpruritic skin since age 6 years in 2000. It notes that the patient had a left axillary lymph node biopsy performed in May, 2010, which was diagnosed as dermatopathic lymphadenopathy. The article discusses Hodgkin lymphoma and...

  • Prognostication and Risk-Adapted Therapy of Hodgkin's Lymphoma Using Positron Emission Tomography. Kasamon, Yvette L. // Advances in Hematology;2011, Vol. 2011, p1 

    The use of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) for response assessment in lymphoma is now widespread. Prognostic information obtained from PET performed after two to three cycles of chemotherapy may guide more individualized, risk-adapted therapeutic strategies....

  • PET Response-Guided Treatment of Hodgkin's Lymphoma: A Review of the Evidence and Active Clinical Trials. Aridgides, Paul; Bogart, Jeffrey; Shapiro, Anna; Gajra, Ajeet // Advances in Hematology;2011, Vol. 2011, p1 

    Risk-adaptive therapy forHodgkin's lymphoma focuses on treatment modifications based on assessment of response. [18F]Fluorodeoxyglucose positron emission tomography (PET) performed during or after completion of chemotherapy is a strong prognostic factor for eventual treatment outcome....

  • The Evolving Role of 18F-FDG PET Scans in Patients with Aggressive non-Hodgkin's Lymphoma. Hosein, Peter J.; Lossos, Izidore S. // European Journal of Clinical & Medical Oncology;2010, Vol. 2 Issue 1, p1 

    Functional imaging by 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) is being increasingly incorporated into the evaluation of patients with aggressive non-Hodgkin lymphoma (NHL). Its use for the initial staging in combination with computed tomography has now become standard....

  • Primary bony non-Hodgkin lymphoma of the cervical spine: a case report. Smith, Zachary A.; Sedrak, Mark F.; Khoo, Larry T. // Journal of Medical Case Reports;2010, Vol. 4 Issue 1, p1 

    Introduction: Non-Hodgkin lymphoma primarily originating from the bone is exceedingly rare. To our knowledge, this is the first report of primary bone lymphoma presenting with progressive cord compression from an origin in the cervical spine. Herein, we discuss the unusual location in this case,...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics