Phytochemical and Antimicrobial Activities of Portulaca Oleracea L

Londonkar, Ramesh; Nayaka, Hanumantappa B
October 2011
Journal of Pharmacy Research;Oct2011, Vol. 4 Issue 10, p3553
Academic Journal
Portulaca Oleracea (Portulacaceae) is an important medicinal plant that have been used in traditional medicine. The aim of present study was to investigate antimicrobial properties of chloroform and ethanol extracts of aerial part of Portulaca Oleracea L. For this purpose, the 40mg/mL concentration of these extracts were assayed against five bacteria and three fungi by agar diffusion method. Synthetic antibiotic were used as control, the bacteria like staphylococcus aureus, Bacillus cereus Klebisiella pneumoniae were the most sensitive species and in fungi, Aspergillus fumigates and Nerospora Crassa were the most sensitive species to the chloroform and Ethanolic extracts of Portulaca Oleracea L, while Pseudomonas aeruginosa was the most resistant to these extracts. Furthermore, Escherichia coli has shown resistance to chloroform extract of this plant. The results of the present study supports the folklore usage of the studied plant and suggest that, this plant extract posses compounds which is having antimicrobial properties and helps in developing antimicrobial agent in the form of drugs for the therapy of infectious diseases caused by pathogens. On the basis of above result it indicates that this plant have a proper antibacterial effect and can be considered as a new source for the development of infectious disease treatment drug. The most active extracts can be subjected to isolation and used for the therapeutic as antimicrobials and also to undertaken further pharmacological studies.


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