Analgesic Activity of Roots of Monochoria vaginalis Presl

Kumar, Gupta Manish; Mukesh, Yadav; Sushil, Suthar; Ravi, Dahiya; Shyam, Kumawat Radhey
January 2012
International Journal of Research in Pharmacy & Science;Jan2012, Vol. 2 Issue 1, p109
Academic Journal
The present study was aimed at evaluation of the analgesic activity of total alcoholic and aqueous extract of root of Monochoria vaginalis P in mice. The alcoholic extract of Monochoria vaginalis P root at a dose of 200 mg/kg body weight has shown significant analgesic activity as compared to aqueous extract. The result of hot plate indicated that the total alcoholic extract shows a significant increase (P<0.01) in reaction time at 2 and 3 hours comparable to the reference drug pentazocin but lesser (P<0.05) at 1 hr. The tail immersion and hot plate test reveal that this plant has high analgesic activity. This is because some form of error may be introduced with the animal handing while the test is being elicited. Both test show highest degree of analgesia in alcoholic extract compared to aqueous extract.


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