TITLE

Update and management of psoriasis: A perspective

AUTHOR(S)
Ramesh, R.; Kumar, Subash Vijaya; Deepthi, E.
PUB. DATE
June 2011
SOURCE
Journal of Pharmacy Research;Jun2011, Vol. 4 Issue 6, p1867
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Psoriasis is a major chronic cutaneous disease in dermatological field. It is characterised by inflammatory, red scaly condition of the skin. For the management of psoriasis, a spectrum of drug treatment pharmacological and non-pharmacological therapy is very essential to improve the high quality life of the patient. The drug treatment which includes topical, phototherapy, conventional systemic treatment and biological agents. Whereas, aim of this study was systematically review the safety and efficacy of the treatment option for among the all type of psoriasis. To identify relevant studies, we searched electronic databases and journals, and contacted experts in the field. This review resulted that, management of psoriasis had challenges. However researchers reported that first line therapies for mild to moderate psoriasis are topical treatment, phototherapy either UVB or UVA. Whereas, second line therapies for moderate to severe psoriasis is oral retinoids. In addition to that, severe psoriasis, the systemic agents may be considered in limited circumstance. Whereas, immunosuppressants have been associated with development of opportunistic infections. Furthermore, alteration in treatment modalities as a result of toxicity concerns, especially with traditional therapy must reoccurs be monitored closely, can result in ongoing cycles of remission and relapse. Many researchers concludes that, no available therapies are curative, disease inevitably recurs when therapy is discontinued, So there is an urgency to develop awareness among the researchers to develop a new molecules to treat psoriatic patient.
ACCESSION #
74457572

 

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